5-aminolevulinic acid fluorescence guided surgery for resection of cystic meningioma with bone invasion

Meningiomas have a 5 year recurrence rate of 8%. Histological grade and extent of resection are the two main prognostic factors. Cystic meningiomas represent between 2 and 4% of meningiomas, and the complete resection rate in these cases is 62.7%. 5-ALA has been shown to be useful in detecting tumou...

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Bibliographic Details
Published in:British journal of neurosurgery 2023-10, Vol.37 (5), p.1223-1227
Main Authors: García Moreno, Rafael, Ippolito Bastidas, Hyaissa, Fernández Portales, Ignacio, Rubio Fernández, Alejandro, Hidalgo Llorca, María, Cabezudo Artero, José Manuel
Format: Article
Language:English
Subjects:
Aged
Aminolevulinic Acid
Brain cancer
Fluorescence
Humans
Meningeal Neoplasms - diagnostic imaging
Meningeal Neoplasms - pathology
Meningeal Neoplasms - surgery
Meningioma - diagnostic imaging
Meningioma - pathology
Meningioma - surgery
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Summary:Meningiomas have a 5 year recurrence rate of 8%. Histological grade and extent of resection are the two main prognostic factors. Cystic meningiomas represent between 2 and 4% of meningiomas, and the complete resection rate in these cases is 62.7%. 5-ALA has been shown to be useful in detecting tumour remnants that could go unnoticed by the conventional microsurgical technique, thereby achieving more complete resections. We present the case of a 66-year-old patient with a frontal convexity meningioma, presenting with a cystic component and bone invasion, who was treated using 5-ALA fluorescence-guided surgery. Fluorescence emission from the tumour tissue allowed the areas of bone invasion and the cystic wall to be identified, achieving complete resection.
ISSN:0268-8697
1360-046X
DOI:10.1080/02688697.2020.1837729