Laugier‐Hunziker syndrome: a case report of the pediatric patient and review of the literature

Laugier‐Hunziker syndrome (LHS) is a rare, idiopathic pigmentary disorder especially affecting the lips and oral mucosa. At present, no more than 200 cases of patients diagnosed with LHS syndrome have been described worldwide. To date, three patients under the age of 20 have been described, includin...

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Bibliographic Details
Published in:International journal of dermatology 2020-12, Vol.59 (12), p.1513-1519
Main Authors: Sputa‐Grzegrzolka, Patrycja, Wozniak, Zdzislaw, Akutko, Katarzyna, Pytrus, Tomasz, Baran, Wojciech, Calik, Jacek, Glatzel‐Plucinska, Natalia, Domagala, Zygmunt, Podhorska‐Okolow, Marzenna, Stawarski, Andrzej, Dziegiel, Piotr
Format: Article
Language:English
Subjects:
Addison's disease
Case reports
Diagnosis
Differential diagnosis
Etiology
Health risks
Hyperpigmentation
Literature reviews
Mucosa
Patients
Signs and symptoms
Skin diseases
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Summary:Laugier‐Hunziker syndrome (LHS) is a rare, idiopathic pigmentary disorder especially affecting the lips and oral mucosa. At present, no more than 200 cases of patients diagnosed with LHS syndrome have been described worldwide. To date, three patients under the age of 20 have been described, including the youngest patient who is a 12‐year‐old child. The exact etiology of LHS still remains uncertain, as there is no evidence of systemic symptoms or increased cancer risk. The final diagnosis of LHS is possible after the exclusion of other, more serious diseases involving skin‐mucosal hyperpigmentation, mainly Peutz‐Jeghers syndrome (PJS) and Addison's disease (AD). Herein, we present a 16‐year‐old patient who has been diagnosed with oral hyperpigmentation since the age of 13. We reviewed the clinical and histological findings. In addition, we discussed the differential diagnosis of mucocutaneous hyperpigmentation.
ISSN:0011-9059
1365-4632
DOI:10.1111/ijd.15262