Serum salusin-β in relation to atherosclerosis and ventricular dysfunction in patients with type 2 diabetes mellitus

Salusin-β is a newly defined biomarker that plays a role in atherogenesis and in homeostasis. The study aimed to assess serum salusin-β level in relation to atherosclerosis and ventricular dysfunction in type 2 diabetes mellitus (T2DM) patients. Sixty T2DM patients and twenty-five age-matched health...

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Bibliographic Details
Published in:Diabetes & metabolic syndrome clinical research & reviews 2020-11, Vol.14 (6), p.2057-2062
Main Authors: Yassien, Marwa, Fawzy, Olfat, Mahmoud, Eman, Khidr, Emad Gamil
Format: Article
Language:English
Subjects:
Atherosclerosis
LV Dysfunction
Salusin-β
Type 2 diabetes
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Summary:Salusin-β is a newly defined biomarker that plays a role in atherogenesis and in homeostasis. The study aimed to assess serum salusin-β level in relation to atherosclerosis and ventricular dysfunction in type 2 diabetes mellitus (T2DM) patients. Sixty T2DM patients and twenty-five age-matched healthy controls were included. Serum salusin-β was determined by ELISA. Echocardiography and carotid ultrasonography were carried out for all individuals. Serum salusin-β level was significantly elevated in patients with T2DM than in controls (P 
ISSN:1871-4021
1878-0334
DOI:10.1016/j.dsx.2020.10.025