Effects of waiting time between failed fresh cycle embryo transfer and the next frozen embryo transfer on pregnancy outcomes in assisted reproductive technology

Objective To explore how waiting time after failed fresh cycle embryo transfer affects the pregnancy outcomes of the next frozen embryo transfer (FET). Methods A retrospective analysis was carried out on the data of women who had received at least one FET after a failed fresh embryo transfer between...

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Published in:International journal of gynecology and obstetrics 2021-05, Vol.153 (2), p.248-253
Main Authors: Tian, Xiao, Song, Jing‐Yan, Sun, Zhen‐Gao
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Language:English
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fresh embryo transfer
pregnancy outcome
waiting time
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cited_by cdi_FETCH-LOGICAL-c3293-39807c3d9753f94cc53846835e60ea684bda1914548e82b69b8cd6c2912d6bdb3
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container_title International journal of gynecology and obstetrics
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creator Tian, Xiao
Song, Jing‐Yan
Sun, Zhen‐Gao
description Objective To explore how waiting time after failed fresh cycle embryo transfer affects the pregnancy outcomes of the next frozen embryo transfer (FET). Methods A retrospective analysis was carried out on the data of women who had received at least one FET after a failed fresh embryo transfer between January 2013 to December 2019. The women were grouped based on the “time” of the first FET, referring to the period between a failed fresh embryo transfer and the beginning of the next cycle of FET. This time is divided into two classes: immediate (
doi_str_mv 10.1002/ijgo.13453
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Methods A retrospective analysis was carried out on the data of women who had received at least one FET after a failed fresh embryo transfer between January 2013 to December 2019. The women were grouped based on the “time” of the first FET, referring to the period between a failed fresh embryo transfer and the beginning of the next cycle of FET. This time is divided into two classes: immediate (&lt;90 days after the failed fresh embryo transfer) and delayed (≥90 days after failed fresh embryo transfer). The following parameters were investigated: clinical pregnancy rate; biochemical pregnancy rate; ectopic pregnancy rate; and non‐pregnancy rate. Results A total of 293 cases of fresh embryo transfer cycles were included. No significant differences in the number of obtained oocytes, total number of FET, and the total amount of gonadotropin were seen between the immediate and delayed fresh embryo transfer groups. The pregnancy outcomes of the two groups were similar. Conclusion The duration of waiting time between failed fresh embryo transfer and the next FET does not affect pregnancy outcomes. Synopsis The duration of waiting time between failed fresh embryo transfer and the next frozen embryo transfer does not affect pregnancy outcomes.</description><identifier>ISSN: 0020-7292</identifier><identifier>EISSN: 1879-3479</identifier><identifier>DOI: 10.1002/ijgo.13453</identifier><identifier>PMID: 33124045</identifier><language>eng</language><publisher>United States</publisher><subject>fresh embryo transfer ; pregnancy outcome ; waiting time</subject><ispartof>International journal of gynecology and obstetrics, 2021-05, Vol.153 (2), p.248-253</ispartof><rights>2020 International Federation of Gynecology and Obstetrics</rights><rights>2020 International Federation of Gynecology and Obstetrics.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3293-39807c3d9753f94cc53846835e60ea684bda1914548e82b69b8cd6c2912d6bdb3</citedby><cites>FETCH-LOGICAL-c3293-39807c3d9753f94cc53846835e60ea684bda1914548e82b69b8cd6c2912d6bdb3</cites><orcidid>0000-0002-9723-1213 ; 0000-0002-2700-017X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33124045$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tian, Xiao</creatorcontrib><creatorcontrib>Song, Jing‐Yan</creatorcontrib><creatorcontrib>Sun, Zhen‐Gao</creatorcontrib><title>Effects of waiting time between failed fresh cycle embryo transfer and the next frozen embryo transfer on pregnancy outcomes in assisted reproductive technology</title><title>International journal of gynecology and obstetrics</title><addtitle>Int J Gynaecol Obstet</addtitle><description>Objective To explore how waiting time after failed fresh cycle embryo transfer affects the pregnancy outcomes of the next frozen embryo transfer (FET). Methods A retrospective analysis was carried out on the data of women who had received at least one FET after a failed fresh embryo transfer between January 2013 to December 2019. The women were grouped based on the “time” of the first FET, referring to the period between a failed fresh embryo transfer and the beginning of the next cycle of FET. This time is divided into two classes: immediate (&lt;90 days after the failed fresh embryo transfer) and delayed (≥90 days after failed fresh embryo transfer). The following parameters were investigated: clinical pregnancy rate; biochemical pregnancy rate; ectopic pregnancy rate; and non‐pregnancy rate. Results A total of 293 cases of fresh embryo transfer cycles were included. No significant differences in the number of obtained oocytes, total number of FET, and the total amount of gonadotropin were seen between the immediate and delayed fresh embryo transfer groups. The pregnancy outcomes of the two groups were similar. Conclusion The duration of waiting time between failed fresh embryo transfer and the next FET does not affect pregnancy outcomes. 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Methods A retrospective analysis was carried out on the data of women who had received at least one FET after a failed fresh embryo transfer between January 2013 to December 2019. The women were grouped based on the “time” of the first FET, referring to the period between a failed fresh embryo transfer and the beginning of the next cycle of FET. This time is divided into two classes: immediate (&lt;90 days after the failed fresh embryo transfer) and delayed (≥90 days after failed fresh embryo transfer). The following parameters were investigated: clinical pregnancy rate; biochemical pregnancy rate; ectopic pregnancy rate; and non‐pregnancy rate. Results A total of 293 cases of fresh embryo transfer cycles were included. No significant differences in the number of obtained oocytes, total number of FET, and the total amount of gonadotropin were seen between the immediate and delayed fresh embryo transfer groups. The pregnancy outcomes of the two groups were similar. Conclusion The duration of waiting time between failed fresh embryo transfer and the next FET does not affect pregnancy outcomes. Synopsis The duration of waiting time between failed fresh embryo transfer and the next frozen embryo transfer does not affect pregnancy outcomes.</abstract><cop>United States</cop><pmid>33124045</pmid><doi>10.1002/ijgo.13453</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-9723-1213</orcidid><orcidid>https://orcid.org/0000-0002-2700-017X</orcidid></addata></record>
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subjects fresh embryo transfer
pregnancy outcome
waiting time
title Effects of waiting time between failed fresh cycle embryo transfer and the next frozen embryo transfer on pregnancy outcomes in assisted reproductive technology
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