Clinical and Radiographic Factors Associated With Failed Renal Angioembolization: Results From the Multi-institutional Genitourinary Trauma Study (Mi-GUTS)

• Published in: Urology (Ridgewood, N.J.) N.J.), 2021-02, Vol.148, p.287-291
• Main Authors: Armas-Phan, Manuel, Keihani, Sorena, Agochukwu-Mmonu, Nnenaya, Cohen, Andrew J., Rogers, Douglas M., Wang, Sherry S., Gross, Joel A., Joyce, Ryan P., Hagedorn, Judith C., Voelzke, Bryan, Moses, Rachel A., Sensenig, Rachel L., Selph, J. Patrick, Gupta, Shubham, Baradaran, Nima, Erickson, Bradley A., Schwartz, Ian, Elliott, Sean P., Mukherjee, Kaushik, Smith, Brian P., Santucci, Richard A., Burks, Frank N., Dodgion, Christopher M., Carrick, Matthew M., Askari, Reza, Majercik, Sarah, Nirula, Raminder, Myers, Jeremy B., Breyer, Benjamin N.
• Format: Article
• Language: English
• Subjects: Adult; Angiography; Embolization, Therapeutic - methods; Female; Humans; Kidney - diagnostic imaging; Kidney - injuries; Male; Middle Aged; Prospective Studies; Treatment Failure; Wounds, Nonpenetrating - diagnostic imaging; Wounds, Nonpenetrating - therapy; Wounds, Penetrating - diagnostic imaging; Wounds, Penetrating - therapy; Young Adult
• ISSN: 0090-4295; 1527-9995
• DOI: 10.1016/j.urology.2020.10.027

To find clinical or radiographic factors that are associated with angioembolization failure after high-grade renal trauma. Patients were selected from the Multi-institutional Genito-Urinary Trauma Study. Included were patients who initially received renal angioembolization after high-grade renal trauma (AAST grades III-V). This cohort was dichotomized into successful or failed angioembolization. Angioembolization was considered a failure if angioembolization was followed by repeat angiography and/or an exploratory laparotomy. A total of 67 patients underwent management initially with angioembolization, with failure in 18 (27%) patients. Those with failed angioembolization had a larger proportion ofgrade IV (72% vs 53%) and grade V (22% vs 12%) renal injuries. A total of 53 patients underwent renal angioembolization and had initial radiographic data for review, with failure in 13 cases. The failed renal angioembolization group had larger perirenal hematoma sizes on the initial trauma scan. Angioembolization after high-grade renal trauma failed in 27% of patients. Failed angioembolization was associated with higher injury grade and a larger perirenal hematoma. Likely these characteristics are associated with high-grade renal trauma that may be less amenable to successful treatment after a single renal angioembolization.