Transcatheter Aortic Valve Replacement With Balloon-Expandable Valves: Comparison of SAPIEN 3 Ultra Versus SAPIEN 3

The aim of this study was to compare outcomes after transcatheter aortic valve replacement (TAVR) with the SAPIEN 3 Ultra (Ultra) and SAPIEN 3 (S3) transcatheter heart valves (THVs). The latest generation balloon-expandable Ultra THV incorporates new technical features and might improve outcomes fol...

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Bibliographic Details
Published in:JACC. Cardiovascular interventions 2020-11, Vol.13 (22), p.2631-2638
Main Authors: Rheude, Tobias, Pellegrini, Costanza, Lutz, Jannik, Alvarez-Covarrubias, Hector A, Lahmann, Anna Lena, Mayr, N Patrick, Michel, Jonathan, Kasel, Markus A, Joner, Michael, Xhepa, Erion
Format: Article
Language:English
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Summary:The aim of this study was to compare outcomes after transcatheter aortic valve replacement (TAVR) with the SAPIEN 3 Ultra (Ultra) and SAPIEN 3 (S3) transcatheter heart valves (THVs). The latest generation balloon-expandable Ultra THV incorporates new technical features and might improve outcomes following TAVR. This registry included all consecutive patients who underwent TAVR with either the Ultra or S3 between January 2014 and January 2020. One-to-one propensity score matching was performed to account for differences in baseline characteristics. In-hospital and 30-day Valve Academic Research Consortium-2-defined outcomes were investigated. A total of 310 patients (n = 155 Ultra, n = 155 S3) were included. There were no significant differences in baseline characteristics after propensity score matching. Procedures were significantly more often performed under conscious sedation with Ultra compared with S3 (97.4% vs. 71.6%; p 
ISSN:1876-7605
DOI:10.1016/j.jcin.2020.07.013