Gut Microbiota in Patients with Morbid Obesity Before and After Bariatric Surgery: a Ten-Year Review Study (2009–2019)

The changes in the composition and function of gut microbiota affect the metabolic functions (which are mediated by microbial effects) in patients with obesity, resulting in significant physiological regulation in these patients. Most of the studies emphasize that the Western-style diet (high fat an...

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Bibliographic Details
Published in:Obesity surgery 2021, Vol.31 (1), p.317-326
Main Authors: Koulas, Spyridon G., Stefanou, Christos K., Stefanou, Stefanos K., Tepelenis, Kostas, Zikos, Nikolaos, Tepetes, Konstantinos, Kapsoritakis, Andreas
Format: Article
Language:English
Subjects:
Bariatric Surgery
Gastrectomy
Gastric Bypass
Gastrointestinal Microbiome
Gastrointestinal surgery
Humans
Medicine
Medicine & Public Health
Metabolic syndrome
Microbiota
Obesity, Morbid - surgery
Review
Surgery
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Summary:The changes in the composition and function of gut microbiota affect the metabolic functions (which are mediated by microbial effects) in patients with obesity, resulting in significant physiological regulation in these patients. Most of the studies emphasize that the Western-style diet (high fat and low vegetable consumption) leads to significant changes in the intestinal microbiome in individuals with metabolic syndrome. A deeper understanding of the profiles of gut microbes will contribute to the development of new therapeutic strategies for the management of metabolic syndrome and other metabolic diseases and related disorders. The aim of this review is to evaluate recent experimental evidence outlining the alterations of gut microbiota composition and function in recovery from bariatric surgical operations with an emphasis on sleeve gastrectomy and gastric bypass.
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-020-05074-2