Association between homocysteine and obesity: A meta‐analysis

According to previous studies of obesity, we found that the association between homocysteine concentrations and obesity was reported controversially. Thus, we carried out this meta‐analysis to investigate this association. We searched PubMed, The Cochrane library, and EMBASE database for studies tha...

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Bibliographic Details
Published in:Journal of evidence-based medicine 2021-09, Vol.14 (3), p.208-217
Main Authors: Wang, Jinxiang, You, Dingyun, Wang, Huaping, Yang, Yanhong, Zhang, Dan, Lv, Junyan, Luo, Sufeng, Liao, Rui, Ma, Lanqing
Format: Article
Language:English
Subjects:
Comorbidity
Homocysteine
Meta-analysis
Obesity
Pathophysiology
Polycystic ovary syndrome
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Summary:According to previous studies of obesity, we found that the association between homocysteine concentrations and obesity was reported controversially. Thus, we carried out this meta‐analysis to investigate this association. We searched PubMed, The Cochrane library, and EMBASE database for studies that evaluate the relationship between homocysteine concentrations and obesity from inception to March, 2019. The quality of all included studies was assessed by the Newcastle Ottawa Scale (NOS) and the Agency for Healthcare Research Quality (AHRQ). The RevMan5.3 software and Stata12.0 software were used for conducting all data analyses. Standardized mean differences (SMD) with the corresponding 95% confidence intervals (95% CIs) were used as a measure of effect size to assess the relationship between homocysteine concentrations and obesity through a meta‐analysis. The level of significance was set at P 
ISSN:1756-5391
1756-5383
1756-5391
DOI:10.1111/jebm.12412