Do knee injection portals affect clinical results of bone marrow aspirate concentrate injection in the treatment of osteoarthritis? A prospective randomized controlled study

To explore the effect that the location of needle placement has on efficacy and tolerability of bone marrow aspirate concentrate injections during treatment of knee osteoarthritis. Bone marrow aspirate concentrate injections were administered to 111 patients via superolateral, anteromedial or antero...

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Bibliographic Details
Published in:Regenerative medicine 2020-08, Vol.15 (8), p.1987-2000
Main Authors: Dulic, Oliver, Lalic, Ivica, Kecojevic, Vaso, Gavrilovic, Gordan, Abazovic, Dzihan, Miskulin, Mladen, Maric, Dusan, Bumbasirevic, Marko
Format: Article
Language:English
Subjects:
bone marrow aspirate concentrate
knee injections
osteoarthritis
portals
stem cells
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Summary:To explore the effect that the location of needle placement has on efficacy and tolerability of bone marrow aspirate concentrate injections during treatment of knee osteoarthritis. Bone marrow aspirate concentrate injections were administered to 111 patients via superolateral, anteromedial or anterolateral portals. Pain was assessed by visual analog scale before and 3, 7, 14 and 21 days after intervention. Knee function was assessed by Western Ontario and McMaster Universities Osteoarthritis Index, Knee Injury and Osteoarthritis Outcome Score and International Knee Documentation Committee scores before and 1, 3, 6, 9 and 12 months after intervention. Significant differences in Western Ontario and McMaster Universities Osteoarthritis Index, Knee Injury and Osteoarthritis Outcome Score and International Knee Documentation Committee scores were observed 12 months post intervention compared with baseline (p 
ISSN:1746-0751
1746-076X
DOI:10.2217/rme-2020-0020