Impact of post‐operative serum albumin level on anastomotic leakage after transthoracic oesophagectomy for oesophageal squamous cell carcinoma

In this study, we reported that serum albumin level on the first post‐operative day was an independent predictor for the occurrence of anastomotic leakage (AL) in patients with oesophageal squamous cell carcinoma who underwent transthoracic oesophagectomy. Patients with low album level post‐operativ...

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Bibliographic Details
Published in:ANZ journal of surgery 2021-01, Vol.91 (1-2), p.E7-E13
Main Authors: Zhuge, Lingdun, Zheng, Difan, Mao, Hengyu, Xiang, Jiaqing, Chen, Haiquan
Format: Article
Language:English
Subjects:
Albumin
Anastomosis
Anastomosis, Surgical - adverse effects
Anastomotic leak
Anastomotic Leak - epidemiology
Anastomotic Leak - etiology
anastomotic leakage
Cancer
Cervix
China - epidemiology
Esophageal cancer
Esophageal Neoplasms - surgery
Esophageal Squamous Cell Carcinoma - surgery
Esophagectomy - adverse effects
Esophagus
Head and Neck Neoplasms
Humans
Leakage
Multivariate analysis
oesophageal squamous cell carcinoma
oesophagectomy
Population studies
Retrospective Studies
Risk analysis
Risk factors
Serum Albumin
Squamous cell carcinoma
Subgroups
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Summary:In this study, we reported that serum albumin level on the first post‐operative day was an independent predictor for the occurrence of anastomotic leakage (AL) in patients with oesophageal squamous cell carcinoma who underwent transthoracic oesophagectomy. Patients with low album level post‐operatively were at higher risk of developing with AL. Increase of albumin level to the normal range post‐operatively could reduce the risk of AL. Background The correlation of post‐operative serum albumin level with the occurrence of anastomotic leakage (AL) in oesophageal squamous cell carcinoma (ESCC) remains unclear. The aim of this study was to evaluate the impact of post‐operative serum albumin level on AL after transthoracic oesophagectomy. Methods Patients with ESCC who underwent transthoracic oesophagectomy between 2013 and 2017 in Fudan University Shanghai Cancer Center were included. The correlation of post‐operative serum albumin level with the occurrence and short‐term outcomes of AL was analysed. Results Patients with serum albumin level of
ISSN:1445-1433
1445-2197
DOI:10.1111/ans.16406