Long-Term Follow-Up of Pericardium for the Ventricular Component in Atrioventricular Septal Defect Repair

Background: Despite the improved outcome in complete atrioventricular septal defect (AVSD) repair, reoperations for left atrioventricular valve (LAVV) dysfunction are common. The aim of this study was to evaluate the effect of fresh untreated autologous pericardium for ventricular septal defect (VSD...

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Published in:World journal for pediatric & congenital heart surgery 2020-11, Vol.11 (6), p.742-747
Main Authors: IJsselhof, Rinske J., Duchateau, Saniyé D. R., Schouten, Rianne M., Slieker, Martijn G., Hazekamp, Mark G., Schoof, Paul H.
Format: Article
Language:English
Subjects:
Animals
Cardiac Surgical Procedures - methods
Cattle
Female
Follow-Up Studies
Heart Septal Defects - diagnosis
Heart Septal Defects - surgery
Humans
Infant
Male
Pericardium - transplantation
Reoperation
Retrospective Studies
Treatment Outcome
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Summary:Background: Despite the improved outcome in complete atrioventricular septal defect (AVSD) repair, reoperations for left atrioventricular valve (LAVV) dysfunction are common. The aim of this study was to evaluate the effect of fresh untreated autologous pericardium for ventricular septal defect (VSD) closure on atrioventricular valve function and compare the results with the use of treated bovine pericardial patch material. Methods: Clinical and echocardiographic data were collected of patients with complete AVSD with their VSD closed with either untreated autologous pericardial or treated bovine pericardial patch material between January 1, 1996, and December 31, 2003. Evaluation closed in September 2019. Results: A total of 77 patients were analyzed (untreated autologous pericardial VSD patch: 59 [77%], treated bovine pericardial VSD patch: 18 [23%]). Median age at surgery was 3.6 (interquartile range [IQR]: 2.7-4.5) months, and median weight was 4.5 (IQR: 3.9-5.1) kg. Trisomy 21 was present in 70 (91%) patients. Median follow-up time was 17.5 (IQR: 12.6-19.8) years. Death
ISSN:2150-1351
2150-136X
DOI:10.1177/2150135120941461