Laparoscopic adenomyomectomy combined with levonorgestrel‐releasing intrauterine system in the treatment of adenomyosis: Feasibility and effectiveness

Aim To evaluate the clinical efficacy and safety of laparoscopic adenomyomectomy combined with intraoperative replacement of levonorgestrel‐releasing intrauterine system (LNG‐IUS) in the treatment of symptomatic adenomyosis. Methods This is a case‐series study in a university medical center. A total...

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Bibliographic Details
Published in:The journal of obstetrics and gynaecology research 2021-02, Vol.47 (2), p.613-620
Main Authors: Sun, Feng, Zhang, Ye, You, Min, Yang, YePing, Yu, YingYing, Xu, Hong
Format: Article
Language:English
Subjects:
adenomyosis
Amenorrhea
conservative surgery
laparoscopic adenomyomectomy
Laparoscopy
levonorgestrel‐releasing intrauterine system
Menstruation
Patients
Side effects
Surgery
Uterus
Vagina
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Summary:Aim To evaluate the clinical efficacy and safety of laparoscopic adenomyomectomy combined with intraoperative replacement of levonorgestrel‐releasing intrauterine system (LNG‐IUS) in the treatment of symptomatic adenomyosis. Methods This is a case‐series study in a university medical center. A total of 52 patients with symptomatic adenomyosis were treated by laparoscopic adenomyomectomy combined with intraoperative replacement of LNG‐IUS from January 2015 to July 2018. Visual analog scale, menstrual flow and uterine volume were compared before and after the surgery (3, 12 and 24 months). Meanwhile, LNG‐IUS‐induced adverse reactions (e.g. irregular vaginal bleeding, amenorrhea, expulsion, and perforation) were also recorded. Results All operations were successfully completed via laparoscopy without conversion to laparotomy. No severe complications were noted during the surgical procedure or follow‐up period. The mean postoperative visual analog scale and menstrual flow scores and the volume of the uterus were significantly decreased (all P 
ISSN:1341-8076
1447-0756
DOI:10.1111/jog.14571