Balantioides coli

• Published in: Research in veterinary science 2021-03, Vol.135, p.424-431
• Main Authors: Ponce-Gordo, Francisco, García-Rodríguez, Juan José
• Format: Article
• Language: English
• Subjects: Animals; Balantioides coli; Birds; Camelidae; Camels; Control measures; Cysts; Diarrhea; Disinfectants; Drinking water; Epidemiology; Farms; Hygiene; Infections; Intestinal microflora; Intestine; Iodoquinol; Large intestine; Life cycles; Metronidazole; Microbiota; Morphology; Natural disasters; Nitroimidazole; Oral administration; Parasites; Sanitation; Secnidazole; Sheep; Symptomatology; Treatment; Veterinary medicine; Wastewater; Wastewater disposal; Water supply
• ISSN: 0034-5288; 1532-2661
• DOI: 10.1016/j.rvsc.2020.10.028

Balantioides coli (=Balantidium coli) is the only ciliate that parasitizes humans. Pigs are the main reservoir. Other species, as camels, cattle, donkey, sheep and goat have been also proposed as reservoirs for human infections. The parasite has a direct life cycle, being transmitted by the faecal-oral route. This type of cycle and the large number of host species imply an important potential for zoonotic transmission of the parasite. Infections are most commonly found in tropical and temperate regions, with prevalence up to 100% in pigs; high prevalence values have been also recorded in some non-human primates and camels. In humans, prevalence is usually under 10% in the population at risk. The main epidemiological factors involved in the transmission of this parasite include close contact with pigs, lack of basic sanitation infrastructures (water supply, wastewater disposal) and hygiene. Individual health status, intestinal microbiota and diet are also important for the onset of the infection. Outbreaks caused by this parasite are rare; those reported to date were related to poor hygienic conditions or to catastrophic natural disasters. Balantioides coli infections can be asymptomatic and symptomatic, which can be chronic (with intermittent diarrhoea), or acute (a dysenteric form which can be life-threatening). Efective treatments include tetracycline, iodoquinol and 5-nitroimidazole compounds (metronidazole, secnidazole). The main effective individual preventive measure is the use of disinfected water for drinking and other uses. Adequate water supply infrastructures, proper disposal of wastewater and animal faeces, and regular monitoring programs on farms will help limit transmission. •Balantioides coli is a waterborne and foodborne parasitic ciliate of worldwide distribution.•The parasite has a wide range of hosts, including humans; main reservoirs are pigs.•The main risk factors are contact with pigs, water contamination and poor hygiene.•Symptomatic cases could lead to host death.•Effective treatments (i.e., tetracycline, iodoquinol, secnidazole) are available.