Incidence of community-acquired pneumonia in urban China: A national population-based study

Community-acquired pneumonia (CAP) is one of the major global health problems worldwide. However, the epidemiological information of CAP is limited in China. This study aimed to estimate the incidence rate of CAP and describe the epidemiologic characteristics among the Chinese population. We conduct...

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Published in:Vaccine 2020-12, Vol.38 (52), p.8362-8370
Main Authors: Sun, Yixin, Li, Hui, Pei, Zhengcun, Wang, Shengfeng, Feng, Jingnan, Xu, Lu, Gao, Pei, Cao, Bin, Zhan, Siyan
Format: Article
Language:English
Subjects:
Age
Aged
Aged, 80 and over
Algorithms
Autumn
Child
Child, Preschool
China - epidemiology
Claim database
Community-Acquired Infections - epidemiology
Community-acquired pneumonia
Coronaviruses
COVID-19
Disease
Epidemiology
Female
Global health
Health problems
Humans
Immunization
Incidence
Influenza
Male
Males
Medical records
Mortality
Patients
Pneumonia
Pneumonia - epidemiology
Population
Population studies
Population-based studies
Provinces
Public health
Retrospective Studies
Vaccines
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creator Sun, Yixin
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Cao, Bin
Zhan, Siyan
description Community-acquired pneumonia (CAP) is one of the major global health problems worldwide. However, the epidemiological information of CAP is limited in China. This study aimed to estimate the incidence rate of CAP and describe the epidemiologic characteristics among the Chinese population. We conducted a retrospective analysis of CAP incidence using the Chinese Urban Basic Medical Insurance database of 23 provinces in 2016, which covered 427.52 million urban beneficiaries of all age groups in Mainland China. CAP episodes were identified using a diagnosis-term-derived algorithm, and multiple CAP records of one single person within 90 continuous days were considered as one single episode. The incidence rates were calculated and described by sex, age, region, and season. A total of 1.42 million patients were identified as having one or more CAP episodes, and finally a sum of 1.48 million CAP episodes were counted. The overall incidence of CAP was 7.13 (95% CI: 6.11–8.15) per 1000 person-years, in males 7.32 (95% CI: 6.28–8.35) and females 6.93 (95% CI: 5.92–7.94) per 1000 person-years, respectively. The incidence varied by age with a U-shaped curve peaking in children aged 
doi_str_mv 10.1016/j.vaccine.2020.11.004
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However, the epidemiological information of CAP is limited in China. This study aimed to estimate the incidence rate of CAP and describe the epidemiologic characteristics among the Chinese population. We conducted a retrospective analysis of CAP incidence using the Chinese Urban Basic Medical Insurance database of 23 provinces in 2016, which covered 427.52 million urban beneficiaries of all age groups in Mainland China. CAP episodes were identified using a diagnosis-term-derived algorithm, and multiple CAP records of one single person within 90 continuous days were considered as one single episode. The incidence rates were calculated and described by sex, age, region, and season. A total of 1.42 million patients were identified as having one or more CAP episodes, and finally a sum of 1.48 million CAP episodes were counted. The overall incidence of CAP was 7.13 (95% CI: 6.11–8.15) per 1000 person-years, in males 7.32 (95% CI: 6.28–8.35) and females 6.93 (95% CI: 5.92–7.94) per 1000 person-years, respectively. The incidence varied by age with a U-shaped curve peaking in children aged &lt; 5 years old [65.80 (95% CI: 62.52–69.08)] and elderly population aged ≥ 80 years old [14.98 (95% CI: 13.63–16.34)]. The incidence varied markedly by regions. Furthermore, the rate showed a clear seasonal trend, which peaked in spring, decreased in summer and autumn, and re-ascended in winter. This study reveals a relatively high level of CAP incidence in China. 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Elsevier Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-e8b62b9311239eea101f068eebc70d95210ad827246584152f6210c49ccaf6cf3</citedby><cites>FETCH-LOGICAL-c393t-e8b62b9311239eea101f068eebc70d95210ad827246584152f6210c49ccaf6cf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33199077$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sun, Yixin</creatorcontrib><creatorcontrib>Li, Hui</creatorcontrib><creatorcontrib>Pei, Zhengcun</creatorcontrib><creatorcontrib>Wang, Shengfeng</creatorcontrib><creatorcontrib>Feng, Jingnan</creatorcontrib><creatorcontrib>Xu, Lu</creatorcontrib><creatorcontrib>Gao, Pei</creatorcontrib><creatorcontrib>Cao, Bin</creatorcontrib><creatorcontrib>Zhan, Siyan</creatorcontrib><title>Incidence of community-acquired pneumonia in urban China: A national population-based study</title><title>Vaccine</title><addtitle>Vaccine</addtitle><description>Community-acquired pneumonia (CAP) is one of the major global health problems worldwide. 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However, the epidemiological information of CAP is limited in China. This study aimed to estimate the incidence rate of CAP and describe the epidemiologic characteristics among the Chinese population. We conducted a retrospective analysis of CAP incidence using the Chinese Urban Basic Medical Insurance database of 23 provinces in 2016, which covered 427.52 million urban beneficiaries of all age groups in Mainland China. CAP episodes were identified using a diagnosis-term-derived algorithm, and multiple CAP records of one single person within 90 continuous days were considered as one single episode. The incidence rates were calculated and described by sex, age, region, and season. A total of 1.42 million patients were identified as having one or more CAP episodes, and finally a sum of 1.48 million CAP episodes were counted. The overall incidence of CAP was 7.13 (95% CI: 6.11–8.15) per 1000 person-years, in males 7.32 (95% CI: 6.28–8.35) and females 6.93 (95% CI: 5.92–7.94) per 1000 person-years, respectively. The incidence varied by age with a U-shaped curve peaking in children aged &lt; 5 years old [65.80 (95% CI: 62.52–69.08)] and elderly population aged ≥ 80 years old [14.98 (95% CI: 13.63–16.34)]. The incidence varied markedly by regions. Furthermore, the rate showed a clear seasonal trend, which peaked in spring, decreased in summer and autumn, and re-ascended in winter. This study reveals a relatively high level of CAP incidence in China. These findings provide baseline data for establishing effective prevention strategies, targeted at susceptible populations, regions, and seasons in China.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>33199077</pmid><doi>10.1016/j.vaccine.2020.11.004</doi><tpages>9</tpages></addata></record>
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source ScienceDirect Journals
subjects Age
Aged
Aged, 80 and over
Algorithms
Autumn
Child
Child, Preschool
China - epidemiology
Claim database
Community-Acquired Infections - epidemiology
Community-acquired pneumonia
Coronaviruses
COVID-19
Disease
Epidemiology
Female
Global health
Health problems
Humans
Immunization
Incidence
Influenza
Male
Males
Medical records
Mortality
Patients
Pneumonia
Pneumonia - epidemiology
Population
Population studies
Population-based studies
Provinces
Public health
Retrospective Studies
Vaccines
title Incidence of community-acquired pneumonia in urban China: A national population-based study
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