Rare case of metastatic liposarcoma to the thyroid gland and a review of the literature of metastatic sarcomas to the thyroid

Background Liposarcomas are the second most common type of soft tissue sarcomas. Typically, myxoid liposarcomas have a metastatic rate of 10%, usually involving the retroperitoneal space, abdomen, and spine. Metastasis to the thyroid is extremely rare. Design/Method A 62‐year‐old male with a history...

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Bibliographic Details
Published in:Head & neck 2021-03, Vol.43 (3), p.E20-E26
Main Authors: Xing, Monica H., Mundi, Neil, Govindan, Aparna, Khorsandi, Azita, Brandwein‐Weber, Margaret, Matloob, Ammar, Liaw, Bobby, Urken, Mark L.
Format: Article
Language:English
Subjects:
Biopsy
Computed tomography
Head and neck
Liposarcoma
Literature reviews
Metastases
Metastasis
myxoid liposarcomas
Nodules
Sarcoma
Thyroid
Thyroid gland
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Summary:Background Liposarcomas are the second most common type of soft tissue sarcomas. Typically, myxoid liposarcomas have a metastatic rate of 10%, usually involving the retroperitoneal space, abdomen, and spine. Metastasis to the thyroid is extremely rare. Design/Method A 62‐year‐old male with a history of metastatic myxoid liposarcoma in his right thigh presented to our clinic for evaluation of a thyroid nodule incidentally identified on a CT scan. A subsequent FNA biopsy was suggestive of a metastatic liposarcoma. Results The patient underwent a left thyroid lobectomy and final pathology confirmed a grade II/III metastatic myxoid liposarcoma that measured 3.3 cm. The patient tolerated the procedure well. Conclusions Our case highlights the role of a patient's medical history when evaluating thyroid nodules to optimize accurate diagnosis, as liposarcomas do not typically metastasize to the thyroid. We also provide an updated review of the literature on all cases of metastatic sarcomas to the thyroid.
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.26552