The expanding arms of Zika virus: An updated review with recent Indian outbreaks

Summary Zika virus (ZIKV) outbreaks and their adverse clinical consequences have raised concerns throughout the world. ZIKV was little known during the initial outbreaks in Yap islands and French Polynesia, but it came to attention after the series of Brazil outbreaks in which severe complications l...

Full description

Saved in:
Bibliographic Details
Published in:Reviews in medical virology 2021-01, Vol.31 (1), p.1-9
Main Authors: Agarwal, Ankita, Chaurasia, Deepti
Format: Article
Language:English
Subjects:
Climatic conditions
Disease Outbreaks
Epidemiology
Humans
India - epidemiology
Infant, Newborn
Microencephaly
Outbreaks
transmission
Vectors
Zika Virus
Zika Virus Infection - epidemiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary Zika virus (ZIKV) outbreaks and their adverse clinical consequences have raised concerns throughout the world. ZIKV was little known during the initial outbreaks in Yap islands and French Polynesia, but it came to attention after the series of Brazil outbreaks in which severe complications like microcephaly in newborn babies was detected. During 2018, outbreaks of ZIKV occurred in two states of India which, being a tropical country, has congenial climatic conditions, abundance of highly competent mosquito vectors such as Aedes aegypti and Aedes albopictus, and an immunologically naïve population. In this review, we will briefly discuss the history, epidemiology, evolution, transmission (vector‐borne and non‐vector borne), pathogenesis, clinical signs and unusual presentations, laboratory diagnosis, treatment, prevention and control of ZIKV. Finally, we suggest priorities for urgent research required to address unanswered questions about Zika infections and help bring this virus under control.
ISSN:1052-9276
1099-1654
DOI:10.1002/rmv.2145