Solitary Testicular Myofibroma in a Rabbit

Myofibromas are mesenchymal tumours of myofibroblastic origin that occur in solitary or multicentric forms. Solitary benign myofibromas mainly occur on the head and neck, especially in the subcutaneous region. They rarely occur in visceral organs in humans, but visceral myofibroma has not been repor...

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Bibliographic Details
Published in:Journal of comparative pathology 2020-10, Vol.180, p.1-4
Main Authors: Kim, Tae-Un, Lee, Sang-Hwa, Jung, Yi-Rang, Kwak, So-Hyun, Jung, Jae Yong, Lee, Seoung-Woo, Baek, Su-Min, Lee, A-Rang, Choi, Seong-Kyoon, Han, Se-Hyeon, Han, Jee Eun, Kim, Tae-Hwan, Jeong, Kyu-Shik, Park, Jin-Kyu
Format: Article
Language:English
Subjects:
myofibroma
rabbit
solitary lesion
testicular tumour
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Summary:Myofibromas are mesenchymal tumours of myofibroblastic origin that occur in solitary or multicentric forms. Solitary benign myofibromas mainly occur on the head and neck, especially in the subcutaneous region. They rarely occur in visceral organs in humans, but visceral myofibroma has not been reported in animals. We now report a case of testicular myofibroma in a 6-year-old rabbit in which orchiectomy revealed an enlarged testis with a multinodular surface. The cut surface of the testis showed a thick, homogeneous white–yellow mass surrounding the testicular parenchyma. Histopathologically, the mass was composed of collagen and eosinophilic fascicles of spindle cells that were immunopositive for α-smooth muscle actin but not desmin, S-100 or von Willebrand factor. These features distinguished the myofibroma from other spindle cell tumours. To the best of our knowledge, this is the first report of solitary testicular myofibroma in any animal species.
ISSN:0021-9975
1532-3129
DOI:10.1016/j.jcpa.2020.07.010