Association of adverse outcomes of intrahepatic cholestasis of pregnancy with zonulin levels

Our aim was to investigate serum zonulin levels in intrahepatic cholestasis of pregnancy (ICP) and to determine the usefulness of zonulin in ICP follow-up. A prospective case-control study was carried out which included 88 pregnant women (44 patients with ICP and 44 controls). Maternal serum samples...

Full description

Saved in:
Bibliographic Details
Published in:Journal of obstetrics and gynaecology 2021-08, Vol.41 (6), p.904-909
Main Authors: Deniz, Cigdem Damla, Ozler, Sibel, Sayın, Fatma Kubra
Format: Article
Language:English
Subjects:
adverse pregnancy outcomes
cholestasis
Clinical outcomes
Gallbladder diseases
increased bile acids
intestinal permeability
Permeability
Pregnancy
Womens health
Zonulin
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Our aim was to investigate serum zonulin levels in intrahepatic cholestasis of pregnancy (ICP) and to determine the usefulness of zonulin in ICP follow-up. A prospective case-control study was carried out which included 88 pregnant women (44 patients with ICP and 44 controls). Maternal serum samples obtained from all participants and zonulin levels were determined by enzyme-linked immunosorbent assay (ELISA). Compared with controls, women with ICP had significantly higher zonulin levels (mean 0.728 ± 0.520 ng/mL vs. 1.303 ± 0.63 ng/mL, p 
ISSN:0144-3615
1364-6893
DOI:10.1080/01443615.2020.1820463