Predictors of neo-aortic valve regurgitation in the long term after arterial switch operation

• Published in: Heart and vessels 2021-05, Vol.36 (5), p.693-703
• Main Authors: Takada, Takuma, Asagai, Seiji, Sato, Masaki, Harada, Gen, Shimada, Eriko, Ishido, Mikiko, Shinohara, Tokuko, Inai, Kei, Hagiwara, Nobuhisa
• Format: Article
• Language: English
• Subjects: Aorta; Aortic valve; Arteries; Biomedical Engineering and Bioengineering; Blood pressure; Cardiac Surgery; Cardiology; Catheterization; Catheters; Children; Evaluation; Heart valves; Hemodynamics; Infants; Medical instruments; Medicine; Medicine & Public Health; Neonates; Original Article; Regurgitation; Sensitivity analysis; Transposition; Vascular Surgery
• ISSN: 0910-8327; 1615-2573
• DOI: 10.1007/s00380-020-01729-3

Although arterial switch operations (ASOs) have been performed globally to repair d-transposition of the great arteries (d-TGA) in neonates and infants, few studies have been reported regarding the influence of the hemodynamics of patients with d-TGA who have undergone ASO on the development of neo-aortic valve regurgitation (AR). We aimed to investigate the relationship between the hemodynamics and development of AR after ASO in patients with d-TGA by catheter evaluation. This observational study screened 114 consecutive patients who underwent ASO for d-TGA or Taussig–Bing anomaly and who subsequently underwent catheter evaluations in our institution. We reviewed their records for the past 20 years and collected their first catheterization data post-ASO in early childhood. Thirty-six post-ASO patients who underwent catheter evaluations in both the early surgical and long-term phases were finally analyzed. Patients were divided into the following groups according to the presence of significant AR in the long-term phase: the AR group ( n  = 9 with AR ≥ grade II by the Sellers classification) and the non-AR group ( n  = 27 with AR