Loading…
Clinical and histological comparison of the soft tissue morphology between zirconia and titanium dental implants under healthy and experimental mucositis conditions—A randomized controlled clinical trial
Objectives To analyse the soft tissue morphology under healthy and experimental mucositis conditions comparing zirconia and titanium implants. Methods Forty‐two patients with two adjacent missing teeth received one zirconia (Zr) and one titanium (Ti) implant, with the mesial and distal position rand...
Saved in:
| Published in: | Journal of clinical periodontology 2021-05, Vol.48 (5), p.721-733 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c3931-43f368a148a500127d2addfcb2bf07e86eeffd5a87eaccc5c28741a4166c22993 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c3931-43f368a148a500127d2addfcb2bf07e86eeffd5a87eaccc5c28741a4166c22993 |
| container_end_page | 733 |
| container_issue | 5 |
| container_start_page | 721 |
| container_title | Journal of clinical periodontology |
| container_volume | 48 |
| creator | Bienz, Stefan P. Hilbe, Monika Hüsler, Jürg Thoma, Daniel S. Hämmerle, Christoph H. F. Jung, Ronald E. |
| description | Objectives
To analyse the soft tissue morphology under healthy and experimental mucositis conditions comparing zirconia and titanium implants.
Methods
Forty‐two patients with two adjacent missing teeth received one zirconia (Zr) and one titanium (Ti) implant, with the mesial and distal position randomized. At 3 months, half of the patients were instructed to continue (healthy; h) and the other half to omit (experimental mucositis; m) oral hygiene around the implants for 3 weeks. Clinical parameters were evaluated before and after the experimental phase, and a soft tissue biopsy was harvested. Mixed model analyses were performed to analyse the data.
Results
The plaque control record increased significantly for the two mucositis groups, reaching 68.3 ± 31.9% (mean ± SD) for Zr‐m and 75.0 ± 29.4% for Ti‐m (p |
| doi_str_mv | 10.1111/jcpe.13411 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2467613303</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2518831321</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3931-43f368a148a500127d2addfcb2bf07e86eeffd5a87eaccc5c28741a4166c22993</originalsourceid><addsrcrecordid>eNp9kUtuFDEQhi0EIpPAhgMgS2xQpA5-9HMZjcJLkWABEruWxy7THrntxnYrTFYcgmtxCU6CezphwQJvXCp_-qv8_wg9o-SC5vNqLye4oLyk9AHa0JqQglT0y0O0IZzwou6a7gSdxrgnhDac88fohHPWtKRsN-jX1hpnpLBYOIUHE5O3_uuxIf04iWCid9hrnAbA0euEk4lxBjz6MA0Le8A7SDcADt-aIL0z4iiVTBLOzCNW4FJWM-NkhUsRz05BwAMIm4bDEYXvEwQzrtw4Sx9NHpLnO5UL7-LvHz8vccioH80tqOUlBW_tUt6vn4IR9gl6pIWN8PTuPkOfX1992r4trj-8ebe9vC4k7zgtSq553QpatqLKprBGMaGUlju206SBtgbQWlWibUBIKSvJ2qakoqR1LRnrOn6GXq66U_DfZoipH02UYPMPwc-xZ2Xd1JRn-zP64h907-fg8nY9q2jbcsoZzdT5SsngYwyg-yk7IsKhp6RfQu6XkPtjyBl-fic570ZQf9H7VDNAV-DGWDj8R6p_v_14tYr-AXpOuWg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2518831321</pqid></control><display><type>article</type><title>Clinical and histological comparison of the soft tissue morphology between zirconia and titanium dental implants under healthy and experimental mucositis conditions—A randomized controlled clinical trial</title><source>Wiley</source><creator>Bienz, Stefan P. ; Hilbe, Monika ; Hüsler, Jürg ; Thoma, Daniel S. ; Hämmerle, Christoph H. F. ; Jung, Ronald E.</creator><creatorcontrib>Bienz, Stefan P. ; Hilbe, Monika ; Hüsler, Jürg ; Thoma, Daniel S. ; Hämmerle, Christoph H. F. ; Jung, Ronald E.</creatorcontrib><description>Objectives
To analyse the soft tissue morphology under healthy and experimental mucositis conditions comparing zirconia and titanium implants.
Methods
Forty‐two patients with two adjacent missing teeth received one zirconia (Zr) and one titanium (Ti) implant, with the mesial and distal position randomized. At 3 months, half of the patients were instructed to continue (healthy; h) and the other half to omit (experimental mucositis; m) oral hygiene around the implants for 3 weeks. Clinical parameters were evaluated before and after the experimental phase, and a soft tissue biopsy was harvested. Mixed model analyses were performed to analyse the data.
Results
The plaque control record increased significantly for the two mucositis groups, reaching 68.3 ± 31.9% (mean ± SD) for Zr‐m and 75.0 ± 29.4% for Ti‐m (p < .0001), being also significantly lower for Zr‐m than for Ti‐m. Bleeding on probing remained stable in group Zr‐m and amounted to 21.7 ± 23.6%, but increased significantly in group Ti‐m (p = .040), measuring 32.5 ± 27.8%. The number of inflammatory cells and the length of the junctional epithelium did not significantly differ between the groups.
Conclusion
Both implants rendered similar outcomes under healthy conditions. Lower plaque and bleeding scores were detected for zirconia implants under experimental mucositis conditions. Histologically, only minimal differences were observed.</description><identifier>ISSN: 0303-6979</identifier><identifier>EISSN: 1600-051X</identifier><identifier>DOI: 10.1111/jcpe.13411</identifier><identifier>PMID: 33278048</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Biopsy ; Bleeding ; Clinical trials ; Dental implants ; Dental Implants - adverse effects ; Dental prosthetics ; Dentistry ; Epithelium ; histology ; histomorphometry ; Humans ; Hygiene ; Inflammation ; Morphology ; Mucositis ; Oral hygiene ; peri‐implant soft tissue ; Titanium ; Transplants & implants ; Zirconia ; zirconia implant ; Zirconium</subject><ispartof>Journal of clinical periodontology, 2021-05, Vol.48 (5), p.721-733</ispartof><rights>2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd</rights><rights>2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.</rights><rights>Copyright © 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3931-43f368a148a500127d2addfcb2bf07e86eeffd5a87eaccc5c28741a4166c22993</citedby><cites>FETCH-LOGICAL-c3931-43f368a148a500127d2addfcb2bf07e86eeffd5a87eaccc5c28741a4166c22993</cites><orcidid>0000-0003-2055-1320 ; 0000-0002-8562-1580 ; 0000-0002-1764-7447</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33278048$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bienz, Stefan P.</creatorcontrib><creatorcontrib>Hilbe, Monika</creatorcontrib><creatorcontrib>Hüsler, Jürg</creatorcontrib><creatorcontrib>Thoma, Daniel S.</creatorcontrib><creatorcontrib>Hämmerle, Christoph H. F.</creatorcontrib><creatorcontrib>Jung, Ronald E.</creatorcontrib><title>Clinical and histological comparison of the soft tissue morphology between zirconia and titanium dental implants under healthy and experimental mucositis conditions—A randomized controlled clinical trial</title><title>Journal of clinical periodontology</title><addtitle>J Clin Periodontol</addtitle><description>Objectives
To analyse the soft tissue morphology under healthy and experimental mucositis conditions comparing zirconia and titanium implants.
Methods
Forty‐two patients with two adjacent missing teeth received one zirconia (Zr) and one titanium (Ti) implant, with the mesial and distal position randomized. At 3 months, half of the patients were instructed to continue (healthy; h) and the other half to omit (experimental mucositis; m) oral hygiene around the implants for 3 weeks. Clinical parameters were evaluated before and after the experimental phase, and a soft tissue biopsy was harvested. Mixed model analyses were performed to analyse the data.
Results
The plaque control record increased significantly for the two mucositis groups, reaching 68.3 ± 31.9% (mean ± SD) for Zr‐m and 75.0 ± 29.4% for Ti‐m (p < .0001), being also significantly lower for Zr‐m than for Ti‐m. Bleeding on probing remained stable in group Zr‐m and amounted to 21.7 ± 23.6%, but increased significantly in group Ti‐m (p = .040), measuring 32.5 ± 27.8%. The number of inflammatory cells and the length of the junctional epithelium did not significantly differ between the groups.
Conclusion
Both implants rendered similar outcomes under healthy conditions. Lower plaque and bleeding scores were detected for zirconia implants under experimental mucositis conditions. Histologically, only minimal differences were observed.</description><subject>Biopsy</subject><subject>Bleeding</subject><subject>Clinical trials</subject><subject>Dental implants</subject><subject>Dental Implants - adverse effects</subject><subject>Dental prosthetics</subject><subject>Dentistry</subject><subject>Epithelium</subject><subject>histology</subject><subject>histomorphometry</subject><subject>Humans</subject><subject>Hygiene</subject><subject>Inflammation</subject><subject>Morphology</subject><subject>Mucositis</subject><subject>Oral hygiene</subject><subject>peri‐implant soft tissue</subject><subject>Titanium</subject><subject>Transplants & implants</subject><subject>Zirconia</subject><subject>zirconia implant</subject><subject>Zirconium</subject><issn>0303-6979</issn><issn>1600-051X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kUtuFDEQhi0EIpPAhgMgS2xQpA5-9HMZjcJLkWABEruWxy7THrntxnYrTFYcgmtxCU6CezphwQJvXCp_-qv8_wg9o-SC5vNqLye4oLyk9AHa0JqQglT0y0O0IZzwou6a7gSdxrgnhDac88fohHPWtKRsN-jX1hpnpLBYOIUHE5O3_uuxIf04iWCid9hrnAbA0euEk4lxBjz6MA0Le8A7SDcADt-aIL0z4iiVTBLOzCNW4FJWM-NkhUsRz05BwAMIm4bDEYXvEwQzrtw4Sx9NHpLnO5UL7-LvHz8vccioH80tqOUlBW_tUt6vn4IR9gl6pIWN8PTuPkOfX1992r4trj-8ebe9vC4k7zgtSq553QpatqLKprBGMaGUlju206SBtgbQWlWibUBIKSvJ2qakoqR1LRnrOn6GXq66U_DfZoipH02UYPMPwc-xZ2Xd1JRn-zP64h907-fg8nY9q2jbcsoZzdT5SsngYwyg-yk7IsKhp6RfQu6XkPtjyBl-fic570ZQf9H7VDNAV-DGWDj8R6p_v_14tYr-AXpOuWg</recordid><startdate>202105</startdate><enddate>202105</enddate><creator>Bienz, Stefan P.</creator><creator>Hilbe, Monika</creator><creator>Hüsler, Jürg</creator><creator>Thoma, Daniel S.</creator><creator>Hämmerle, Christoph H. F.</creator><creator>Jung, Ronald E.</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2055-1320</orcidid><orcidid>https://orcid.org/0000-0002-8562-1580</orcidid><orcidid>https://orcid.org/0000-0002-1764-7447</orcidid></search><sort><creationdate>202105</creationdate><title>Clinical and histological comparison of the soft tissue morphology between zirconia and titanium dental implants under healthy and experimental mucositis conditions—A randomized controlled clinical trial</title><author>Bienz, Stefan P. ; Hilbe, Monika ; Hüsler, Jürg ; Thoma, Daniel S. ; Hämmerle, Christoph H. F. ; Jung, Ronald E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3931-43f368a148a500127d2addfcb2bf07e86eeffd5a87eaccc5c28741a4166c22993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Biopsy</topic><topic>Bleeding</topic><topic>Clinical trials</topic><topic>Dental implants</topic><topic>Dental Implants - adverse effects</topic><topic>Dental prosthetics</topic><topic>Dentistry</topic><topic>Epithelium</topic><topic>histology</topic><topic>histomorphometry</topic><topic>Humans</topic><topic>Hygiene</topic><topic>Inflammation</topic><topic>Morphology</topic><topic>Mucositis</topic><topic>Oral hygiene</topic><topic>peri‐implant soft tissue</topic><topic>Titanium</topic><topic>Transplants & implants</topic><topic>Zirconia</topic><topic>zirconia implant</topic><topic>Zirconium</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bienz, Stefan P.</creatorcontrib><creatorcontrib>Hilbe, Monika</creatorcontrib><creatorcontrib>Hüsler, Jürg</creatorcontrib><creatorcontrib>Thoma, Daniel S.</creatorcontrib><creatorcontrib>Hämmerle, Christoph H. F.</creatorcontrib><creatorcontrib>Jung, Ronald E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical periodontology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bienz, Stefan P.</au><au>Hilbe, Monika</au><au>Hüsler, Jürg</au><au>Thoma, Daniel S.</au><au>Hämmerle, Christoph H. F.</au><au>Jung, Ronald E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical and histological comparison of the soft tissue morphology between zirconia and titanium dental implants under healthy and experimental mucositis conditions—A randomized controlled clinical trial</atitle><jtitle>Journal of clinical periodontology</jtitle><addtitle>J Clin Periodontol</addtitle><date>2021-05</date><risdate>2021</risdate><volume>48</volume><issue>5</issue><spage>721</spage><epage>733</epage><pages>721-733</pages><issn>0303-6979</issn><eissn>1600-051X</eissn><abstract>Objectives
To analyse the soft tissue morphology under healthy and experimental mucositis conditions comparing zirconia and titanium implants.
Methods
Forty‐two patients with two adjacent missing teeth received one zirconia (Zr) and one titanium (Ti) implant, with the mesial and distal position randomized. At 3 months, half of the patients were instructed to continue (healthy; h) and the other half to omit (experimental mucositis; m) oral hygiene around the implants for 3 weeks. Clinical parameters were evaluated before and after the experimental phase, and a soft tissue biopsy was harvested. Mixed model analyses were performed to analyse the data.
Results
The plaque control record increased significantly for the two mucositis groups, reaching 68.3 ± 31.9% (mean ± SD) for Zr‐m and 75.0 ± 29.4% for Ti‐m (p < .0001), being also significantly lower for Zr‐m than for Ti‐m. Bleeding on probing remained stable in group Zr‐m and amounted to 21.7 ± 23.6%, but increased significantly in group Ti‐m (p = .040), measuring 32.5 ± 27.8%. The number of inflammatory cells and the length of the junctional epithelium did not significantly differ between the groups.
Conclusion
Both implants rendered similar outcomes under healthy conditions. Lower plaque and bleeding scores were detected for zirconia implants under experimental mucositis conditions. Histologically, only minimal differences were observed.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>33278048</pmid><doi>10.1111/jcpe.13411</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0003-2055-1320</orcidid><orcidid>https://orcid.org/0000-0002-8562-1580</orcidid><orcidid>https://orcid.org/0000-0002-1764-7447</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0303-6979 |
| ispartof | Journal of clinical periodontology, 2021-05, Vol.48 (5), p.721-733 |
| issn | 0303-6979 1600-051X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2467613303 |
| source | Wiley |
| subjects | Biopsy Bleeding Clinical trials Dental implants Dental Implants - adverse effects Dental prosthetics Dentistry Epithelium histology histomorphometry Humans Hygiene Inflammation Morphology Mucositis Oral hygiene peri‐implant soft tissue Titanium Transplants & implants Zirconia zirconia implant Zirconium |
| title | Clinical and histological comparison of the soft tissue morphology between zirconia and titanium dental implants under healthy and experimental mucositis conditions—A randomized controlled clinical trial |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T09%3A51%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20and%20histological%20comparison%20of%20the%20soft%20tissue%20morphology%20between%20zirconia%20and%20titanium%20dental%20implants%20under%20healthy%20and%20experimental%20mucositis%20conditions%E2%80%94A%20randomized%20controlled%20clinical%20trial&rft.jtitle=Journal%20of%20clinical%20periodontology&rft.au=Bienz,%20Stefan%20P.&rft.date=2021-05&rft.volume=48&rft.issue=5&rft.spage=721&rft.epage=733&rft.pages=721-733&rft.issn=0303-6979&rft.eissn=1600-051X&rft_id=info:doi/10.1111/jcpe.13411&rft_dat=%3Cproquest_cross%3E2518831321%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3931-43f368a148a500127d2addfcb2bf07e86eeffd5a87eaccc5c28741a4166c22993%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2518831321&rft_id=info:pmid/33278048&rfr_iscdi=true |