Ectatic diseases

Ectatic corneal disease (ECD) comprises a group of disorders characterized by progressive thinning and subsequent bulging of the corneal structure. Different phenotypes have been recognized, including keratoglobus, pellucid marginal degeneration (PMD), and keratoconus (KC). Keratoconus has been wide...

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Bibliographic Details
Published in:Experimental eye research 2021-01, Vol.202, p.108347-108347, Article 108347
Main Authors: Salomão, Marcella Q., Hofling- Lima, Ana Luisa, Gomes Esporcatte, Louise Pellegrino, Correa, Fernando Faria, Lopes, Bernardo, Sena, Nelson, Dawson, Daniel G., Ambrósio, Renato
Format: Article
Language:English
Subjects:
Cornea - pathology
Cornea - physiopathology
Corneal biomechanics
Corneal Diseases - pathology
Corneal Diseases - physiopathology
Corneal ectasia
Corneal tomography
Corneal Topography
Elasticity
Humans
Keratoconus
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Summary:Ectatic corneal disease (ECD) comprises a group of disorders characterized by progressive thinning and subsequent bulging of the corneal structure. Different phenotypes have been recognized, including keratoglobus, pellucid marginal degeneration (PMD), and keratoconus (KC). Keratoconus has been widely investigated throughout the years, but the advent of laser refractive surgery boosted an immediate need for more knowledge and research about ectatic diseases. This article discusses nomenclature of ectatic disease, etiology and pathogenesis, along with treatment options, with special focus ok KC and forme fruste keratoconus. •This article contains current data on ectatic diseases.•We discuss the etiology and pathogenesis of ectasia.•Current diagnostic methods for corneal ectasia are discussed.•Current treatments are presented and discussed. Future trends are discussed.
ISSN:0014-4835
1096-0007
DOI:10.1016/j.exer.2020.108347