Younger Age as a Risk Factor for Gynecologic Cancer-related Lymphedema: A Systematic Review

Treatment of gynecologic cancers may lead to the development of lower limb lymphedema. As the course of lymphedema is chronic and progressive, early diagnosis plays a significant role in decreasing morbidity. Therefore, risk assessment is of utmost importance. In this study, we aimed to investigate...

Full description

Saved in:
Bibliographic Details
Published in:Anticancer research 2020-12, Vol.40 (12), p.6609-6612
Main Authors: Guliyeva, Gunel, Huayllani, Maria T, Avila, Francisco R, Boczar, Daniel, Lu, Xiaona, Forte, Antonio Jorge
Format: Article
Language:English
Subjects:
Age
Age Factors
Aged
Cancer
Female
Genital Neoplasms, Female - complications
Health risks
Humans
Incidence
Lymphedema
Lymphedema - epidemiology
Lymphedema - etiology
Middle Aged
Morbidity
Risk analysis
Risk assessment
Risk Factors
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Treatment of gynecologic cancers may lead to the development of lower limb lymphedema. As the course of lymphedema is chronic and progressive, early diagnosis plays a significant role in decreasing morbidity. Therefore, risk assessment is of utmost importance. In this study, we aimed to investigate the impact of age on lymphedema development after treatment for gynecologic cancers. The search of 3 databases (PubMed, Scopus, and Cochrane) revealed 7 relevant articles, which reported either odds ratios or hazard ratios as an outcome measure. A positive relationship between younger age and lower limb lymphedema was shown by 3 articles, while 2 noted increased incidence with older age. The remaining articles reported no significant relationship. Younger age is a risk factor for gynecologic cancer-related lymphedema. However, as individual studies have not included all types of gynecologic cancers, results may not be generalizable.
ISSN:0250-7005
1791-7530
DOI:10.21873/anticanres.14685