Management of Boerhaave syndrome in Australasia: a retrospective case series and systematic review of the Australasian literature

• Published in: ANZ journal of surgery 2021-07, Vol.91 (7-8), p.1376-1384
• Main Authors: Allaway, Matthew G. R., Morris, Paul D., B. Sinclair, Jane‐Louise, Richardson, Arthur J., Johnston, Emma S., Hollands, Michael J.
• Format: Article
• Language: English
• Subjects: Australasia; Boerhaave syndrome; Case reports; Complications; Esophageal Perforation - surgery; Esophagectomy; Esophagus; Humans; Literature reviews; Management; Mediastinal Diseases - surgery; oesophageal rupture; Ostomy; Patients; Retrospective Studies; Systematic review
• ISSN: 1445-1433; 1445-2197
• DOI: 10.1111/ans.16501

Background Boerhaave syndrome is a rare and life‐threatening condition characterized by a spontaneous transmural tear of the oesophagus. There remains wide variation in the condition's management with non‐operative management (NOM) and surgery being the two main treatment strategies. The aim was to review the presentation, management and outcomes for patients treated for Boerhaave syndrome at our institution and to compare these data with that previously reported within the Australasian literature. Methods A retrospective case series was performed for consecutive patients diagnosed with Boerhaave syndrome at our institution between January 2000 and January 2020. A systematic review of the Australasian literature was also performed. Results In case series, 15 patients were included (n = 2 NOM, n = 13 operative). The most common operative technique was primary repair with intercostal drainage via thoracotomy. Major complications occurred in 11 (73%) patients. Median Comprehensive Complication Index was 53.4 (interquartile range: 50). There was a significantly lower Comprehensive Complication Index associated with primary repair when compared to oesophageal resection (P = 0.01). There was one death, in the operative management group. Median length of hospital stay was 33 days (interquartile range: 58). In systematic review, 11 articles were included; four case series and seven case reports. From these, 23 patients met inclusion criteria. The majority of patients (83%) were managed operatively, with only four undergoing NOM. Seven patients died, representing an overall mortality rate of 30%. Conclusions We provide an updated overview of the management of Boerhaave syndrome within Australasia. Aggressive operative management is associated with reasonable outcomes. The primary aim of this study was to assess the management and outcomes for patients diagnosed with Boerhaave syndrome within Australasia. Both a retrospective case series and systematic review of the Australasian literature were performed. We provide an updated overview of the management of Boerhaave syndrome within Australasia.