Vertical rectus abdominis flap (VRAM) for perineal reconstruction following pelvic surgery: A systematic review

• Published in: Journal of plastic, reconstructive & aesthetic surgery reconstructive & aesthetic surgery, 2021-03, Vol.74 (3), p.523-529
• Main Authors: Radwan, Rami W, Tang, Alethea M, Harries, Rhiannon L, Davies, Eleanor G, Drew, Peter, Evans, Martyn D
• Format: Article
• Language: English
• Subjects: APER; Exenteration; Humans; Myocutaneous Flap - transplantation; Pelvic Exenteration - adverse effects; Pelvic Exenteration - methods; Pelvic surgery; Pelvis - surgery; Perineal defect; Perineum - surgery; Postoperative Complications - classification; Postoperative Complications - etiology; Reconstructive Surgical Procedures - adverse effects; Reconstructive Surgical Procedures - methods; Rectus Abdominis - transplantation; Risk Assessment; Treatment Outcome; VRAM flap
• ISSN: 1748-6815; 1878-0539
• DOI: 10.1016/j.bjps.2020.10.100

The vertical rectus abdominis myocutaneous (VRAM) flap is an established technique employed to reconstruct pelvic and perineal defects not amenable to primary closure. The aim of this study was to systematically review the morbidity of VRAM flap reconstruction following exenterative pelvic surgery. A systematic literature search was conducted by using Medline, EMBASE, and Cochrane databases. Abstracts of all studies published from inception to November 2019 were identified. Search terms used included ‘vertical rectus abdominis myocutaneous’, ‘vertical rectus abdominis musculocutaneous’ and ‘VRAM’. Only studies that described outcomes when a VRAM flap was used during exenterative pelvic surgery were included; case reports were excluded. The primary outcome measure was VRAM flap morbidity. Secondary outcome measures included donor site morbidity and hospital length of stay. Sixty-five studies with a total of 1827 patients were identified and included. Perineal reconstruction was most commonly performed following abdominal perineal excision of the rectum (APER) (n = 636 and 34.8%). Median patient age at surgery ranged from 38 to 78 years. Mean perineal flap morbidity was 27%, with a complete flap loss rate of 1.8% and a perineal hernia rate of 0.2%. Mean donor site morbidity was 15%, with an abdominal dehiscence rate of 5.5% and an incisional hernia rate of 3.3%. While overall morbidity after VRAM flap reconstruction in pelvic visceral surgery is high; the risk of major complications remains low. These data are important when counselling patients for surgery.