Comparison the effect of bupivacaine plus magnesium sulfate with ropivacaine plus magnesium sulfate infiltration on postoperative pain in patients undergoing lumbar laminectomy with general anesthesia

In this study, we investigated the effect of local injection of ropivacaine and bupivacaine with magnesium sulfate on postoperative pain in vertebral laminectomy surgery. This randomized double-blind prospective study was conducted among 60 patients aged 18-65 years old with ASA class I and II. Grou...

Full description

Saved in:
Bibliographic Details
Published in:British journal of neurosurgery 2024-04, Vol.ahead-of-print (ahead-of-print), p.1-4
Main Authors: Sane, Shahryar, Mahdkhah, Ata, Golabi, Parang, Hesami, Seyyed Adnan, Kazemi haki, Behzad
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Anesthesia, General
Anesthetics, Local - therapeutic use
Bupivacaine
Bupivacaine - therapeutic use
Double-Blind Method
Humans
Laminectomy - adverse effects
lumbar laminectomy
magnesium sulfate
Magnesium Sulfate - therapeutic use
Middle Aged
Pain, Postoperative - drug therapy
Pain, Postoperative - prevention & control
postoperative pain
Prospective Studies
Ropivacaine
Saline Solution
Surgery
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this study, we investigated the effect of local injection of ropivacaine and bupivacaine with magnesium sulfate on postoperative pain in vertebral laminectomy surgery. This randomized double-blind prospective study was conducted among 60 patients aged 18-65 years old with ASA class I and II. Group RM: (30 people) received 70 mg ropivacaine (14 ml) plus 1 ml magnesium sulfate (500 mg) volume up to 20 ml with normal saline. Group BM: (30 people) received 70 mg bupivacaine (14 ml) plus 1 ml magnesium sulfate (500 mg) volume up to 20 ml with normal saline. The results were analyzed by SPSS 23 software, and statistical analysis consisted of χ 2 test and t-test, and a p value less than .05 was considered significant. Mean pain score based on VAS in 6 and 12 h after surgery in the RM group was lower in the BM group (p  0.05). This study showed that wound infiltration with ropivacaine and magnesium sulfate compared to bupivacaine and magnesium sulfate provided better postoperative analgesia and significantly reduced postoperative opioid consumption in patients undergoing lumbar laminectomy.
ISSN:0268-8697
1360-046X
DOI:10.1080/02688697.2020.1861430