Identification of the factors associated with post-treatment asymptomatic neurosyphilis in HIV-negative patients with serological non-response syphilis: a retrospective study

Some syphilis patients do not exhibit an appropriate serological response after treatment despite the absence of any clinical evidence of treatment failure or reinfection. This condition is called “serofast syphilis” or “serological non-response syphilis.” This study explored the incidence of asympt...

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Bibliographic Details
Published in:International journal of STD & AIDS 2021-03, Vol.32 (4), p.331-335
Main Authors: Weng, Wenjia, Hou, Jiahua, Song, Bingbing, Zhang, Ming, Zhang, Tong, Gao, Yanqing
Format: Article
Language:English
Subjects:
AIDS/HIV
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Summary:Some syphilis patients do not exhibit an appropriate serological response after treatment despite the absence of any clinical evidence of treatment failure or reinfection. This condition is called “serofast syphilis” or “serological non-response syphilis.” This study explored the incidence of asymptomatic neurosyphilis (ANS) and related factors in 324 asymptomatic patients with serological non-response syphilis. We analyzed descriptive statistics stratified by the presence of asymptomatic neurosyphilis for the basic characteristics of samples. Bivariate analysis was conducted to assess correlations between outcomes and potential predictors. Variables significant in the bivariate analysis (p
ISSN:0956-4624
1758-1052
DOI:10.1177/0956462420965850