Geographic and Socioeconomic Factors on Survival in Esthesioneuroblastoma

Objectives Esthesioneuroblastoma (ENB) is a rare sinonasal malignancy with little known regarding how regional and socioeconomic differences in the United States alter disease survival. The aim of this study is to explore the geographic difference in clinical features, socioeconomic factors, and sur...

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Bibliographic Details
Published in:The Laryngoscope 2021-07, Vol.131 (7), p.E2162-E2168
Main Authors: Mikhael, Sandra T., Tadrosse, Abanoob F., Tadrosse, Marina F., Yassa, Arsany, Mikhael, Mina T., Barinsky, Gregory L., Grube, Jordon G., Fang, Christina H., Eloy, Jean Anderson
Format: Article
Language:English
Subjects:
Esthesioneuroblastoma
geographic region
Geography
Head & neck cancer
Laryngoscopy
SEER
sinonasal cancer
socioeconomic
Socioeconomic factors
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Summary:Objectives Esthesioneuroblastoma (ENB) is a rare sinonasal malignancy with little known regarding how regional and socioeconomic differences in the United States alter disease survival. The aim of this study is to explore the geographic difference in clinical features, socioeconomic factors, and survival outcomes of ENB patients. Methods ENB cases were extracted from the Surveillance, Epidemiology, and End Results registry from 1975–2016. Patient data were stratified based on geographical location and comparative analyses of socioeconomic features, disease characteristics, and survival patterns were performed. Kaplan–Meier regression analyses were used to estimate disease‐specific survival (DSS). Results A total of 987 patients were identified: 56.4% West, 14.0% South, 12.7% Midwest, and 16.6% East. The West had the highest proportion of patients with Medicaid coverage (P 
ISSN:0023-852X
1531-4995
DOI:10.1002/lary.29228