Effectiveness of metronidazole gel and mobile telephone short-message service reminders on gingivitis in orthodontic patients

To compare the effectiveness of metronidazole gel and mobile telephone short-message service (SMS) reminders on gingivitis in patients undergoing fixed orthodontic treatment. The trial was double blinded (patient and investigator), and only the clinical trial unit pharmacist was unblinded. Data were...

Full description

Saved in:
Bibliographic Details
Published in:The Angle orthodontist 2021-03, Vol.91 (2), p.220-226
Main Authors: Mahmood, Hafiz Taha, Fatima, Farheen, Fida, Mubassar, Sukhia, Rashna Hoshang, Irfan, Sarah, Malik, Durreshahwar, Younus, Ashfaq, Afzal, Erum
Format: Article
Language:English
Subjects:
Dental Plaque Index
Dentistry
Gingivitis - drug therapy
Gingivitis - prevention & control
Humans
Metronidazole
Oral Hygiene
Periodontal Index
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To compare the effectiveness of metronidazole gel and mobile telephone short-message service (SMS) reminders on gingivitis in patients undergoing fixed orthodontic treatment. The trial was double blinded (patient and investigator), and only the clinical trial unit pharmacist was unblinded. Data were collected from patients undergoing fixed orthodontic treatment for at least 6 months. A total of 66 patients were randomly assigned to either 0.8% metronidazole gel (n = 22), SMS reminder and placebo gel (n = 22), or placebo (control) group only (n = 22). Gingival index (GI), bleeding index (BI), and orthodontic plaque index (OPI) were evaluated on several teeth at baseline (T0) and after 4 weeks (T1). Paired-sample t-tests were used to compare mean differences of indexes at T0 and T1 in the groups, and independent-sample t-tests were used to determine the effects of interventions compared with the controls. Data from 64 patients were analyzed; there were 2 dropouts. There were statistically significant (P < .05) reductions in GI, BI, and OPI scores from T0 to T1 for each intervention. However, there were no significant differences between each intervention and the control group. There were no adverse effects. The null hypothesis could not be rejected. There is no difference between interventions (application of 0.8% metronidazole gel and SMS reminder for reinforcing oral hygiene) in reducing gingival inflammation in orthodontic patients.
ISSN:0003-3219
1945-7103
DOI:10.2319/052920-490.1