Useful preoperative examination findings to classify the grade of ovarian primary mucinous tumor

Purpose To evaluate various imaging features on magnetic resonance imaging (MRI) and tumor markers and their utility to assess various grades of ovarian primary mucinous tumors (OPMTs): benign, borderline, or malignant. Methods Ninety-five pathologically diagnosed OPMTs [53 benign, 24 borderline mal...

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Bibliographic Details
Published in:Abdominal imaging 2021-06, Vol.46 (6), p.2393-2402
Main Authors: Ohya, Ayumi, Ichinohe, Fumihito, Matoba, Hisanori, Kobara, Hisanori, Fujinaga, Yasunari
Format: Article
Language:English
Subjects:
Antigens
Carbohydrates
Carcinoembryonic antigen
Computed tomography
Cysts
Diagnosis
Gastroenterology
Hepatology
Imaging
Lesions
Magnetic resonance imaging
Malignancy
Medical imaging
Medicine
Medicine & Public Health
Ovaries
Pelvis
Quality
Radiology
Tumor markers
Tumors
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Summary:Purpose To evaluate various imaging features on magnetic resonance imaging (MRI) and tumor markers and their utility to assess various grades of ovarian primary mucinous tumors (OPMTs): benign, borderline, or malignant. Methods Ninety-five pathologically diagnosed OPMTs [53 benign, 24 borderline malignant (BM), and 18 malignant] were selected in this retrospective study. MRI features of the ovarian mass, namely the maximum diameter, honeycomb loculi, solid components (SC), stained-glass pattern, and signal intensity of the cyst on T1- (T1WI) and T2-weighted imaging (T2WI) with/without fat suppression, and preoperative STMs, namely carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9, and CA125, were compared between the three tumor grades using univariate analysis. We also analyzed the findings to estimate the pathological diagnosis using classification tree (CT) analysis. Results Maximum diameter, honeycomb loculi, SC, stained-glass pattern, signal intensity of the cyst [hyperintensity on both T1WI and T2WI (T1-hyper/T2-hyper), and hyperintense on T1WI and hypointense on T2WI (T1-hyper/T2-hypo)], and CEA and CA 19-9 concentrations were significantly different between the three tumor grades ( p  
ISSN:2366-004X
2366-0058
DOI:10.1007/s00261-020-02918-4