Clinical characteristic and epidemiological features of SARS CoV‐2 disease patients from a COVID‐19 designated hospital in New Delhi

• Published in: Journal of Medical Virology 2021-04, Vol.93 (4), p.2487-2492
• Main Authors: Saxena, Sonal, Manchanda, Vikas, Sagar, Tanu, Nagi, Nazia, Siddiqui, Oves, Yadav, Abhishek, Arora, Nitin, Hasan, Faria, Meena, Kavita, Bharti, Pradeep, Rana, Neha, Hayat, Sikander, Tuteja, Sanchita, Yadav, Ajeet, Puri, Devyani, Pumma, Palak, Khyati, , Arora, Ananya, Jainandra, , Shreya, Sunidhi, Kumar, Suresh, Sharma, Nandini
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Antigens; Child; Child, Preschool; Chronic illnesses; Comorbidity; Coronary artery disease; coronavirus disease; Coronaviruses; Cough; Cough - virology; COVID-19; COVID-19 - diagnosis; COVID-19 - epidemiology; Diabetes; Diabetes mellitus; Diagnosis; Dyspnea; Epidemiology; Evolution; Female; Fever; Fever - epidemiology; Fever - virology; Heart diseases; Humans; Hypertension; India - epidemiology; Infections; Kidney diseases; Kidneys; Lung diseases; Lungs; Male; Medical records; Middle Aged; Pandemics; Patients; Pharyngitis; Pharyngitis - epidemiology; Pharyngitis - virology; Polymerase chain reaction; Respiratory diseases; SARS-CoV-2; Severe acute respiratory syndrome; Severe acute respiratory syndrome coronavirus 2; Signs and symptoms; Statistical analysis; Statistical methods; Tertiary Care Centers - statistics & numerical data; Viral diseases; Virology; Young Adult
• ISSN: 0146-6615; 1096-9071; 1096-9071
• DOI: 10.1002/jmv.26777

Severe acute respiratory syndrome coronavirus 2 (SARS CoV‐2) infection is rapidly evolving as a serious global pandemic. The present study describes the clinical characteristics of SARS CoV‐2 infection patients. The samples were subjected to reverse‐transcription polymerase chain reaction or Rapid Antigen test for diagnosis of SARS CoV‐2. A cohort of 3745 patients with confirmed diagnosis of SARS CoV‐2 infection in a tertiary care center in New Delhi, India were included in this study. Data were collected from offline and online medical records over a period of 6 months. Amongst 3745 SARS CoV‐2 infected patients, 2245 (60%) were symptomatic and 1500 (40%) were asymptomatic. Most common presenting symptom was cough (49.3%) followed febrile episodes (47.1%), breathlessness (42.7%), and sore throat (35.1%). Cough along with breathlessness (24.1) was the most common combination of symptoms followed by fever with cough (22.7). The most common comorbidity found among symptomatic group was diabetes (42.5%) followed by hypertension (21.4%) and chronic kidney disease (18%). Comorbidities like diabetes mellitus, chronic diseases of lungs, heart, and kidneys were found to be common in symptomatic group and this was found to be statistically significant (p