Dysphagia in a Cancer Patient

Hypercalcemia causes gastrointestinal symptoms such as anorexia, constipation, and pancreatitis but has not been commonly associated with dysphagia. In patients with cancer, dysphagia has been attributed to local tumor invasion or as a complication from surgery, radiotherapy, and chemotherapy. Howev...

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Bibliographic Details
Published in:Dysphagia 2022-02, Vol.37 (1), p.1-3
Main Authors: Villavicencio Kim, Jaimy, Saraceni, Corey, Vaziri, Haleh
Format: Article
Language:English
Subjects:
Anorexia
Calcium
Cancer patients
Care and treatment
Chemotherapy
Clinical Conundrum
Constipation
Deglutition disorders
Deglutition Disorders - complications
Development and progression
Disodium pamidronate
Dysphagia
Excitability
Gastroenterology
Hepatology
Humans
Hypercalcemia
Hypercalcemia - complications
Hypercalcemia - diagnosis
Hypotonicity
Imaging
Malignancy
Medicine
Medicine & Public Health
Neoplasms - complications
Otorhinolaryngology
Pancreatitis
Patients
Radiation therapy
Radiology
Tumors
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Description
Summary:Hypercalcemia causes gastrointestinal symptoms such as anorexia, constipation, and pancreatitis but has not been commonly associated with dysphagia. In patients with cancer, dysphagia has been attributed to local tumor invasion or as a complication from surgery, radiotherapy, and chemotherapy. However, there are cases of dysphagia in setting of malignancy with rapid resolution of symptoms after treatment of hypercalcemia. Excess calcium reduces neuromuscular excitability and leads to hypotonicity of the muscle, which could be mechanism by which dysphagia occurs. There are not enough data about dysphagia in association with hypercalcemia from benign etiologies, which could be due to less pronounced hypercalcemia.
ISSN:0179-051X
1432-0460
DOI:10.1007/s00455-020-10227-7