Bioprinting for the Biologist

Building tissues from scratch to explore entirely new cell configurations could revolutionize fundamental understanding in biology. Bioprinting is an emerging technology to do this. Although typically applied to engineer tissues for therapeutic tissue repair or drug screening, there are many opportu...

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Bibliographic Details
Published in:Cell 2021-01, Vol.184 (1), p.18-32
Main Authors: Daly, Andrew C., Prendergast, Margaret E., Hughes, Alex J., Burdick, Jason A.
Format: Article
Language:English
Subjects:
Biology
Bioprinting
Disease
Humans
Ink
Tissue Engineering
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Summary:Building tissues from scratch to explore entirely new cell configurations could revolutionize fundamental understanding in biology. Bioprinting is an emerging technology to do this. Although typically applied to engineer tissues for therapeutic tissue repair or drug screening, there are many opportunities for bioprinting within biology, such as for exploring cellular crosstalk or cellular morphogenesis. The overall goals of this Primer are to provide an overview of bioprinting with the biologist in mind, outline the steps in extrusion bioprinting (the most widely used and accessible technology), and discuss alternative bioprinting technologies and future opportunities for bioprinting in biology. An exploration of the kinds of biological questions bioprinting can be used to address is paired with practical steps to getting started and recent technological advances.
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2020.12.002