Red Blood Cell Distribution Width (RDW) Correlates to the Anatomical Location of Colorectal Cancer. Implications for Clinical Use

Purpose The pathological, clinical, and therapeutic features of colorectal cancer (CRC) depend on its anatomical localization. We investigated possible associations between the red blood cell distribution width (RDW) and CRC localization. Methods Two-hundred eighty-eight consecutive patients with CR...

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Bibliographic Details
Published in:Journal of gastrointestinal cancer 2022-06, Vol.53 (2), p.259-264
Main Authors: Fancellu, Alessandro, Zinellu, Angelo, Mangoni, Arduino Aleksander, Popova, Anastasia, Galotti, Francesca, Feo, Claudio Francesco, Attene, Federico, Cossu, Antonio, Palmieri, Giuseppe, Paliogiannis, Panagiotis
Format: Article
Language:English
Subjects:
Cancer Research
Colorectal Neoplasms - pathology
Erythrocyte Indices
Erythrocytes - pathology
Gastroenterology
Hemoglobins
Humans
Internal Medicine
Medicine
Medicine & Public Health
Oncology
Original Research
Radiotherapy
Retrospective Studies
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Summary:Purpose The pathological, clinical, and therapeutic features of colorectal cancer (CRC) depend on its anatomical localization. We investigated possible associations between the red blood cell distribution width (RDW) and CRC localization. Methods Two-hundred eighty-eight consecutive patients with CRC were retrospectively studied. Demographic, clinical, pathological and laboratory data were retrieved from clinical records and reports. Results Median RDW values were significantly higher in patients with right-sided CRC when compared to those with CRC in other localizations (16.2, IQR: 14.5–20.0 vs 13.8, IQR: 13.0–16.1, p  
ISSN:1941-6628
1941-6636
DOI:10.1007/s12029-021-00582-5