Tunable Collective Dynamics of Active Inclusions in Viscous Membranes

We study hydrodynamic interactions and clustering mechanisms of active membrane inclusions within lipid bilayers. Pairs of inclusions display unique oscillatory dynamics that disappear when the 3D fluid adjacent to the membrane is confined. We reduce the governing equations to a coupled dynamical sy...

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Bibliographic Details
Published in:Physical review letters 2020-12, Vol.125 (26), p.268101-268101, Article 268101
Main Author: Manikantan, Harishankar
Format: Article
Language:English
Subjects:
Cell Membrane - chemistry
Clustering
Confinement
Hydrodynamics
Inclusions
Lipid Bilayers - chemistry
Lipids
Membranes
Models, Biological
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Summary:We study hydrodynamic interactions and clustering mechanisms of active membrane inclusions within lipid bilayers. Pairs of inclusions display unique oscillatory dynamics that disappear when the 3D fluid adjacent to the membrane is confined. We reduce the governing equations to a coupled dynamical system whose phase behavior reveals the striking role of bulk confinement in enhancing cluster formation within the membrane. Using numerical simulations, we then extend this finding to demonstrate the role of confinement in controlling large-scale aggregation of membrane inclusions.
ISSN:0031-9007
1079-7114
DOI:10.1103/PhysRevLett.125.268101