Ultrasound characterization of the nail bed in patients with systemic lupus erythematosus

Objective To characterize the ultrasound findings of the nail plate and nail bed in systemic lupus erythematosus (SLE) and its association with nail dystrophy. Methods Thirty-two SLE patients, 36 patients with osteoarthritis (OA) and 20 healthy individuals were studied. High-frequency linear ultraso...

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Bibliographic Details
Published in:Lupus 2021-04, Vol.30 (4), p.608-614
Main Authors: Ferrusquia-Toriz, Diana, Hernández-Díaz, Cristina, Amezcua-Guerra, Luis M, Ventura-Ríos, Lucio, Higuera-Ortiz, Violeta, Lozada-Navarro, Ana C, Silveira, Luis H
Format: Article
Language:English
Subjects:
Autoantibodies
Dystrophy
Inhibitor drugs
Lupus
Osteoarthritis
Synovitis
Systemic lupus erythematosus
Ultrasonic imaging
Ultrasound
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Summary:Objective To characterize the ultrasound findings of the nail plate and nail bed in systemic lupus erythematosus (SLE) and its association with nail dystrophy. Methods Thirty-two SLE patients, 36 patients with osteoarthritis (OA) and 20 healthy individuals were studied. High-frequency linear ultrasound was performed in nails of the second to fifth fingers in all participants. Disease activity (SLEDAI-2K index), accrued organ damage (SLICC/ACR index), autoantibody profile, and Raynaud’s phenomenon were also assessed in SLE patients. Results Nail bed thickness in SLE patients was higher than in healthy individuals (1.25 ± 0.31 mm vs 1.17 ± 0.29 mm; P = 0.01) but lower than in OA (1.39 ± 0.37 mm; P 
ISSN:0961-2033
1477-0962
DOI:10.1177/0961203320988609