Loading…

Genetic characterization of acute myeloid leukemia patients with mutations in IDH1/2 genes

•IDH1/2 cases account for 23% of the studied cohort.•Mutual exclusivity was confirmed for IDH1 and IDH2 mutations.•IDH1 (86%) and IDH2 (89%) mutations frequently constitute an ancestral event.

Saved in:
Bibliographic Details
Published in:Leukemia research 2021-02, Vol.101, p.106492-106492, Article 106492
Main Authors: Acha, Pamela, Hoyos, Montserrat, Pratcorona, Marta, Fuster-Tormo, Francisco, Palomo, Laura, Ortega, Esther, Zamora, Lurdes, Vives, Susana, Granada, Isabel, Montoro, Julia, Garcia, Antoni, Arnan, Montserrat, Cervera, Marta, Canet, Marta, Gallardo, David, Arenillas, Leonor, Esteve, Jordi, Baragay, Joan, Salamero, Olga, Motlló, Cristina, Ortín, Xavier, Sierra, Jordi, Solé, Francesc
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:•IDH1/2 cases account for 23% of the studied cohort.•Mutual exclusivity was confirmed for IDH1 and IDH2 mutations.•IDH1 (86%) and IDH2 (89%) mutations frequently constitute an ancestral event.
ISSN:0145-2126
1873-5835
DOI:10.1016/j.leukres.2020.106492