Comparative Study of Chemical Composition, Cholinesterase Inhibition and Antioxidant Potential of Mentha pulegium L. Essential Oil

Perennial plant Mentha pulegium L. (pennyroyal, Lamiaceae) can be found in Europe and Mediterranean. In areas where it thrives, M. pulegium is used in nutrition and as medicinal plant. Essential oil of M. pulegium is also a frequent constituent of foods and fragrances, because of mint‐like odor. Reg...

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Bibliographic Details
Published in:Chemistry & biodiversity 2021-03, Vol.18 (3), p.e2000935-n/a
Main Authors: Bektašević, Mejra, Politeo, Olivera, Carev, Ivana
Format: Article
Language:English
Subjects:
Alzheimer's disease
Antioxidants
Biological activity
Chemical activity
Chemical composition
Cholinesterase
cholinesterase inhibitors
Comparative studies
Essential oils
Free radicals
Herbal medicine
Lipids
Medical treatment
Medicinal plants
Mentha pulegium
Mentha pulegium L
Menthone
Neurodegenerative diseases
Nutrition
Odor
Odors
Oils & fats
Piperitenone
Pulegone
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Summary:Perennial plant Mentha pulegium L. (pennyroyal, Lamiaceae) can be found in Europe and Mediterranean. In areas where it thrives, M. pulegium is used in nutrition and as medicinal plant. Essential oil of M. pulegium is also a frequent constituent of foods and fragrances, because of mint‐like odor. Regarding the use of M. pulegium in traditional medicine and nutrition, as well as fact that essential oils are potential sources of bioactive components, this study was conducted to examine the chemical composition of essential oil of M. pulegium wild growing in Bosnia and Herzegovina and its biological activity. The chemical profile testing was made using GC/MS and GC/FID technique. Potential of cholinesterase inhibition was tested by Ellman's assay. The antioxidant activity was tested by DPPH and FRAP assay. The dominant components in analyzed oil were pulegone 54.4 %, p‐menthone 14.0 % and piperitenone 12.8 %. Good antioxidant activity and moderate cholinesterase inhibition potential of tested essential oil indicates to possibility of its use in treatment of diseases related to free radicals, Alzheimer disease and as lipid protecting antioxidant.
ISSN:1612-1872
1612-1880
DOI:10.1002/cbdv.202000935