In-vitro functional efficacy of extracts from Phyllanthus emblica, Eucalyptus globulus, Tinospora cordifolia as pancreatic lipase inhibitor and source of anti-oxidant in goat meat nuggets

• Published in: Food chemistry 2021-06, Vol.348, p.129087-129087, Article 129087
• Main Authors: Chauhan, Pranav, Kumar, Rajiv Ranjan, Mendiratta, Sanjod Kumar, Talukder, Suman, Gangwar, Mukesh, Sakunde, Deepali T., Meshram, Somesh Kumar
• Format: Article
• Language: English
• Subjects: Animals; Antioxidant; Antioxidants - analysis; Antioxidants - pharmacology; Eucalyptus - chemistry; Eucalyptus globulus; Fat paradox; Goat meat nuggets; Goats; In-vitro digestion; Lipase - antagonists & inhibitors; Pancreas - enzymology; Pancreatic lipase inhibition; Phyllanthus emblica; Phyllanthus emblica - chemistry; Plant Extracts - analysis; Plant Extracts - pharmacology; Red Meat - analysis; Tinospora - chemistry; Tinospora cordifolia
• ISSN: 0308-8146; 1873-7072
• DOI: 10.1016/j.foodchem.2021.129087

•Plant extracts had pancreatic lipase inhibition and anti-oxidant activities.•In-vitro study revealed the impairment of fat digestion in goat meat nuggets.•Order of activities were Phyllanthus emblica > Eucalyptus globulus > Tinospora cordifolia.•Phyllanthus emblica can be a promising natural alternate of orlistat and BHT. The present study was aimed to evaluate the functional efficacy of plant extracts as a source of pancreatic lipase inhibitor and antioxidant in goat meat nuggets to address the fat paradox issue of red meat. The PPLIA, antioxidant potential, and resistance against fat digestion were in the order ofPhyllanthus emblica > Eucalyptus globulus > Tinospora cordifolia.PPL inhibition activities of water and ethanolic extracts fromPhyllanthus emblicausing DNPB and Triolein as substrate were 63.76, 67.94 and 56.17 and 64.36 percent respectively whereas, TPC, DPPH RSA, FRPA were 40.82 and 59.52 (mgGAE/g), 54.89 and 59.84 (percent), 1.26 and 1.61 (OD) respectively. The average diameter of fat globules in digest was maximum (8.91 µm) withPhyllanthus emblicafruits extracts whereas; TBARs (0.347 mg MDA/Kg) and FFA (4.47 µg/g) values were lowest. This study showed that extracts from plants can act as a promising natural alternative in the development of healthy meat products.