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Sarcomatoid larynx carcinoma differential clinical evolution, on field statistical considerations
Spindle cell larynx carcinoma (SpCC) represents around 3% of laryngeal cancers. It is originated by a single cancer stem cell undergoing epithelial to mesenchymal transition. This explains the aggressiveness, the peculiar resistance to conventional therapy and the frequent relapses. We focused on th...
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| Published in: | American journal of otolaryngology 2021-05, Vol.42 (3), p.102934-102934, Article 102934 |
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| container_end_page | 102934 |
| container_issue | 3 |
| container_start_page | 102934 |
| container_title | American journal of otolaryngology |
| container_volume | 42 |
| creator | Ricciardiello, Filippo Bocchetti, Marco Pellini, Raul Palladino, Remo Caraglia, Michele Boscaino, Amedeo Petruzzi, Gerardo Romano, Francesco Jacopo Chiurazzi, Bruno Addeo, Raffaele Mazzone, Salvatore Mesolella, Massimo Oliva, Flavia Iorio, Brigida |
| description | Spindle cell larynx carcinoma (SpCC) represents around 3% of laryngeal cancers. It is originated by a single cancer stem cell undergoing epithelial to mesenchymal transition. This explains the aggressiveness, the peculiar resistance to conventional therapy and the frequent relapses. We focused on this particular cancer subset characteristics in patients, in early and advanced stages primarily aiming to define and highlight the differences with Laryngeal Squamous Cell Carcinoma (LSCC) focusing on clinical features, treatments, follow-up and survival in a patient's cohort composed by comparable cases from two subgroups. |
| doi_str_mv | 10.1016/j.amjoto.2021.102934 |
| format | article |
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| source | ScienceDirect Journals |
| subjects | Cancer Disease Laryngeal cancer Larynx Mesenchyme Mortality Otolaryngology Patients Sarcoma Spidle cell carcinoma Squamous cell carcinoma Statistical analysis Stem cells Subgroups Survival Survival analysis Tumors Variables |
| title | Sarcomatoid larynx carcinoma differential clinical evolution, on field statistical considerations |
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