Association Between Obstructive Sleep Apnea and Diabetic Macular Edema in Patients with Type 2 Diabetes

To evaluate the relationship between obstructive sleep apnea (OSA) and diabetic macular edema (DME) and the effect of OSA on refractory DME in patients with type 2 diabetes (T2DM). Retrospective clinical cohort study. A population-based study was conducted at Chang Gung Memorial Hospital from March...

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Bibliographic Details
Published in:American journal of ophthalmology 2021-06, Vol.226, p.217-225
Main Authors: Chiang, Jui-Fan, Sun, Ming-Hui, Chen, Kuan-Jen, Wu, Wei-Chi, Lai, Chi-Chun, Chang, Chee-Jen, Lin, Yu-Jr, Chang, Shu-Chen, Huang, Hung-Yu, Chen, Ning-Hung, Li, Hsueh-Yu
Format: Article
Language:English
Subjects:
Blood pressure
Body mass index
Cholesterol
Demographics
Diabetes
Diabetic retinopathy
Edema
Electroencephalography
Hypertension
Laboratories
Medical records
Patients
Permeability
Sleep apnea
Survival analysis
Vascular endothelial growth factor
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Summary:To evaluate the relationship between obstructive sleep apnea (OSA) and diabetic macular edema (DME) and the effect of OSA on refractory DME in patients with type 2 diabetes (T2DM). Retrospective clinical cohort study. A population-based study was conducted at Chang Gung Memorial Hospital from March 1, 2009, to March 1, 2020. Among 14,152 patients who had undergone polysomnography (PSG) and whose data were registered on the sleep center's PSG database, 121 patients (242 eyes) with T2DM were enrolled according to the International Classification of Diseases, Ninth Revision (ICD-9) code 3620 for diabetic retinopathy (DR). Patients with a secondary cause of macular edema and those lacking medical records were excluded. All patients with T2DM enrolled in our study received both optical coherence tomography (OCT) and PSG. The prevalence of severe (apnea-hypopnea index [AHI] ≥30) and nonsevere (AHI
ISSN:0002-9394
1879-1891
DOI:10.1016/j.ajo.2021.01.022