A Retrospective Analysis of the Impact of Bariatric Surgery on the Management of Chronic Migraine

Purpose To investigate the association of the two most common bariatric surgical procedures, vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB), with sustained remission from chronic migraine. Materials and Methods Using IBM MarketScan® research database to examine inpatient and p...

Full description

Saved in:
Bibliographic Details
Published in:Obesity surgery 2021-05, Vol.31 (5), p.2040-2049
Main Authors: Nudotor, Richard, Yusuf, Hasiya, Lasisi, Owulatobi, Salia, Emmanuella, Khalifa, Banda, Abbey, Enoch, Oduwole, Modupe, Ayeh, Samuel, Appiafo, Obeng, Canner, Joseph, Scheimann, Ann, Steele, Kimberley E.
Format: Article
Language:English
Subjects:
Aged
Bariatric Surgery
Female
Gastrectomy
Gastric Bypass
Gastrointestinal surgery
Humans
Medicine
Medicine & Public Health
Migraine Disorders - drug therapy
Obesity, Morbid - surgery
Original Contributions
Retrospective Studies
Surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose To investigate the association of the two most common bariatric surgical procedures, vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB), with sustained remission from chronic migraine. Materials and Methods Using IBM MarketScan® research database to examine inpatient and pharmacy claims from 2010 through 2017. A cohort of bariatric patients with chronic migraine was created using inclusion and exclusion criteria. Remission was defined as no refill of first-line migraine medication for 180 days after a patients’ medication was expected to run out, and recurrence as medication refill after at least 180 days of remission. Results Of 1680 patients in our cohort, 931 (55.4%) experienced remission of migraine. Of these, 462 (49.6%) had undergone VSG, while 469 (50.4%) had undergone RYGB. Patients who underwent RYGB had an 11% (RR = 1.11, 95% CI: 1.05, 1.17) increase in likelihood of remission of migraine and a 20% (RR = 0.80, 95% CI: 0.63, 1.04) decrease in likelihood of recurrence of migraine compared to patients who underwent VSG. Older age group, higher number of medications at time of surgery, and female sex were associated with a decreased likelihood of remission. Conclusion Type of bariatric procedure, age, number of medications at surgery, and sex were the most important predictors of migraine remission after surgery.
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-020-05204-w