Air filtration as a tool for the reduction of viral aerosols

• Published in: The Science of the total environment 2021-06, Vol.772, p.144956-144956, Article 144956
• Main Authors: Zacharias, Nicole, Haag, Alexandra, Brang-Lamprecht, Regina, Gebel, Jürgen, Essert, Sarah M., Kistemann, Thomas, Exner, Martin, Mutters, Nico T., Engelhart, Steffen
• Format: Article
• Language: English
• Subjects: Aerosols; Air Filters; Air purification; Bacteriophages; COVID-19; Filtration; phiX174; Transmission; Viruses
• ISSN: 0048-9697; 1879-1026
• DOI: 10.1016/j.scitotenv.2021.144956

For testing the effectiveness of air purification devices in regard to the reduction of virus-containing aerosols, a test method involving test viruses has been lacking until now. The use of bacteriophages (phiX174 phages) is a method to test the efficiency of air purification devices under experimental conditions. Using air purifiers with a HEPA filter H14, a 4.6–6.1 Log reduction of test viruses can be achieved if bacteriophages are directly aerosolised into the air purifier, which corresponds to a reduction of 99.9974–99.9999%. Due to the complexity and individuality of air flow, an experimental approach was used in which all outside influences were minimised. The experimental setup was practical and chosen to project a scenario of direct transmission by an emitting source to a recipient. The experiments were performed with and without the air purifier at a distance of 0.75 m and 1.5 m each. Using the air purifier at a setting of 1000 m3/h, the concentration of the phiX174 phages in the air could be reduced by 2.86 Log (mean value). Nevertheless, the experiments without the air purifier showed a similar reduction rate of 2.61 Log (mean value) after 35 min. The concentration of phiX174 phages in the air could be additionally reduced up to 1 log step (maximum value) by the use of the air purifier in comparison to the experiments without. Distance was shown to be an important factor for risk reduction. [Display omitted] •Use of bacteriophages is suitable to test air purification devices under experimental conditions.•Using air purifiers with HEPA filters, a reduction of test viruses 99.997–99.999% can be achieved.•The application of air purifiers is not able to stop direct transmission.•Maintaining distance is an important risk-reducing factor for the transmission of viral aerosols.•The use of mobile air purifiers cannot replace other safety measures already in implementation.