Risk factors influencing postoperative outcome in patients with perforated peptic ulcer: a prospective cohort study

Background Perforated peptic ulcer (PPU) has been associated with substantially high incidence of morbidity and mortality. The aim of this study was to analyze the factors affecting the outcome of patients having perforated peptic ulcer undergoing surgical intervention. Materials and methods Medical...

Full description

Saved in:
Bibliographic Details
Published in:European journal of trauma and emergency surgery (Munich : 2007) 2022-02, Vol.48 (1), p.81-86
Main Authors: Ahmed, Meraj, Mansoor, Tariq, Rab, Atia Zakaur, Rizvi, Syed Amjad Ali
Format: Article
Language:English
Subjects:
Cohort analysis
Comorbidity
Creatinine
Critical Care Medicine
Emergency medical care
Emergency Medicine
Humans
Incidence
Intensive
Medicine
Medicine & Public Health
Middle Aged
Morbidity
Mortality
Original Article
Peptic Ulcer Perforation - epidemiology
Peptic Ulcer Perforation - surgery
Postoperative Complications - epidemiology
Postoperative period
Prospective Studies
Retrospective Studies
Risk Factors
Sports Medicine
Surgery
Surgical Orthopedics
Traumatic Surgery
Ulcers
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Perforated peptic ulcer (PPU) has been associated with substantially high incidence of morbidity and mortality. The aim of this study was to analyze the factors affecting the outcome of patients having perforated peptic ulcer undergoing surgical intervention. Materials and methods Medical records of 112 patients with PPU who underwent emergency laparotomy between December 2014 and November 2016 were prospectively analyzed. Primary suture of the perforation and pedicled omentoplasty was done in all the patients. Data regarding patients was collected and correlated with the postoperative outcome. Results The overall postoperative morbidity and mortality were 62.5% and 30.4%, respectively. On univariate analysis advanced age (≥ 60 years) [( p  = 0.005), (OR = 3.6), (95% CI = 1.5–8.8)], pre-operative shock [( p   24 h) [( p  = 0.007), (OR = 4.0), (95% CI = 1.5–11.2)] and raised serum creatinine [( p  
ISSN:1863-9933
1863-9941
DOI:10.1007/s00068-020-01597-6