Mild and Selective Rhodium-Catalyzed Transfer Hydrogenation of Functionalized Arenes

Diboron-mediated rhodium-catalyzed transfer hydrogenation of functionalized arenes is reported. In addition to good functional group tolerance, the reaction features operational simplicity and controllable chemoselectivity. The general applicability of this procedure is demonstrated by the selective...

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Bibliographic Details
Published in:Organic letters 2021-03, Vol.23 (5), p.1910-1914
Main Authors: Wang, Yuhan, Chang, Zhiqian, Hu, Yan, Lin, Xiao, Dou, Xiaowei
Format: Article
Language:English
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Summary:Diboron-mediated rhodium-catalyzed transfer hydrogenation of functionalized arenes is reported. In addition to good functional group tolerance, the reaction features operational simplicity and controllable chemoselectivity. The general applicability of this procedure is demonstrated by the selective hydrogenation of a range of arenes, including functionalized benzenes, biphenyls, and polyaromatics.
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.1c00341