The utility of preoperative echocardiography in pediatric obstructive sleep apnea

• Published in: Sleep & breathing 2021-12, Vol.25 (4), p.2171-2178
• Main Authors: Pettitt-Schieber, Brian, Tey, Ching Siong, Hill, Robert, Vaughn, William, Pakanati, Vivek, Leu, Roberta, Raol, Nikhila
• Format: Article
• Language: English
• Subjects: Adolescent; Adverse events; Apnea; Child; Child, Preschool; Children; Coronary artery disease; Dentistry; Echocardiography; Echocardiography - standards; ENT • Original Article; Female; Heart Defects, Congenital - diagnosis; Heart diseases; Heart Diseases - diagnosis; Humans; Infant; Internal Medicine; Male; Medicine; Medicine & Public Health; Neurology; Neuromuscular diseases; Ostomy; Otorhinolaryngology; Outcome and Process Assessment, Health Care; Patients; Pediatrics; Pneumology/Respiratory System; Postoperative Complications - diagnosis; Preoperative Care - standards; Severity of Illness Index; Sleep; Sleep apnea; Sleep Apnea, Obstructive - surgery; Sleep disorders; Tracheostomy
• ISSN: 1520-9512; 1522-1709
• DOI: 10.1007/s11325-021-02303-5

Purpose The purpose of this study was to determine the associations between cardiac function and postoperative adverse events in pediatric patients with obstructive sleep apnea (OSA). Methods Patients between birth and 18 years of age diagnosed with OSA between January 1, 2015, and December 31, 2018, who underwent echocardiographic evaluation within 6 months of surgery at a tertiary care children’s hospital were evaluated. Exclusion criteria included history of neuromuscular disorders, tracheostomy placement, or a predominance of central apneic events recorded during polysomnography (PSG). Patients were grouped by OSA severity. Chi-squared analysis and logistic regression were utilized to determine associations between demographic characteristics, OSA severity, preoperative echocardiographic abnormalities, and postoperative adverse events. Results One hundred ten children met inclusion criteria for the study, including 22 with mild OSA, 22 with moderate OSA, and 66 with severe OSA. Race and the presence of congenital heart disease (CHD) were significantly associated with differences in OSA severity. Echocardiographic abnormalities were found in 45 patients, but exclusion of patients with CHD revealed no significant associations with differences in OSA severity. Postoperative adverse events were identified in 18 (16%) patients, and only O 2 saturation nadir was found to be a significant predictor of these complications. Conclusion Preoperative echocardiogram abnormalities are not commonly found in children with OSA and presence of abnormalities does not predict postoperative adverse events. O 2 saturation nadir measured on preoperative PSG is a significant predictor of postoperative adverse events and should be examined as a clinical indicator of OSA severity.