Routine third‐trimester ultrasound for the detection of small‐for‐gestational age in low‐risk pregnancies (ROTTUS study): randomized controlled trial

ABSTRACT Objective To compare the proportion of small‐for‐gestational‐age (SGA) infants detected by routine third‐trimester ultrasound vs those detected by selective ultrasound based on serial symphysis–fundus height (SFH) measurements (standard care) in low‐risk pregnancy. Methods This was an open‐...

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Bibliographic Details
Published in:Ultrasound in obstetrics & gynecology 2021-06, Vol.57 (6), p.910-916
Main Authors: Wanyonyi, S. Z., Orwa, J., Ozelle, H., Martinez, J., Atsali, E., Vinayak, S., Temmerman, M., Figueras, F.
Format: Article
Language:English
Subjects:
Adult
Birth weight
Childbirth & labor
Clinical trials
Diagnostic Tests, Routine
Female
fetal growth restriction
Fetal Growth Retardation - diagnostic imaging
Fetuses
Gestation
Gestational age
Gynecology
Humans
Infant, Newborn
Infant, Small for Gestational Age
Infants
low‐risk pregnancy
Neonates
Obstetrics
Performance prediction
Predictive Value of Tests
Pregnancy
Pregnancy Trimester, Third
Risk
Risk assessment
ROC Curve
small‐for‐gestational age
third‐trimester ultrasound
Ultrasonic imaging
Ultrasonography, Prenatal
Ultrasound
Weight
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Summary:ABSTRACT Objective To compare the proportion of small‐for‐gestational‐age (SGA) infants detected by routine third‐trimester ultrasound vs those detected by selective ultrasound based on serial symphysis–fundus height (SFH) measurements (standard care) in low‐risk pregnancy. Methods This was an open‐label randomized controlled trial conducted at a hospital in Kenya between May 2018 and February 2020. Low‐risk pregnant women were randomly allocated (ratio of 1:1) to routine ultrasound for fetal growth assessment between 36 + 0 and 37 + 6 weeks' gestation (intervention group) or to standard care, which involved a selective growth scan on clinical suspicion of fetal growth abnormality based on serial SFH measurements (control group). During ultrasound examination, fetal growth was assessed by measurement of the abdominal circumference (AC), and AC
ISSN:0960-7692
1469-0705
DOI:10.1002/uog.23618