Factors Associated with Poor Outcomes in Patients Undergoing Endovascular Therapy for Acute Ischemic Stroke due to Large-Vessel Occlusion in Acute Anterior Circulation: A Retrospective Study

• Published in: World neurosurgery 2021-05, Vol.149, p.e128-e134
• Main Authors: Zhang, Yi-He, Shi, Ming-Chao, Wang, Zhong-Xiu, Li, Chao, Sun, Meng-Yao, Zhou, Jie, Zhang, Wen-Bin, Huo, Long-Wen, Wang, Shou-Chun
• Format: Article
• Language: English
• Subjects: Cerebral infarction; Large-vessel occlusion; Outcome; Reperfusion; Stroke; Thrombectomy
• ISSN: 1878-8750; 1878-8769
• DOI: 10.1016/j.wneu.2021.02.064

To investigate factors associated with poor clinical outcomes in patients with acute ischemic stroke undergoing endovascular therapy. A retrospective review of 265 patients with acute ischemic stroke treated in the First Hospital of Jilin University between January 1, 2016, and November 1, 2019, was performed. The primary outcome was the proportion of patients with a modified Rankin score of 0–2 at 90 days. Univariate and multivariate analyses were performed to assess potential clinical factors associated with a poor 90-day outcome. The rates of successful revascularization, good prognosis, symptomatic intracranial hemorrhage, and mortality were 84.5%, 46.0%, 9.8%, and 12.8%, respectively. As per univariate analysis, age, diagnosis of atrial fibrillation, diagnosis of diabetes, high baseline glucose level, tandem occlusion, high National Institutes of Health Stroke Scale (NIHSS) score at admission, general anesthesia, number of passes, high NIHSS score on discharge, unsuccessful recanalization (modified treatment in cerebral ischemia score