Potential impact of Helicobacter pylori-related metabolic syndrome and Galectin-3 on liver, chronic kidney and brain disorders

•Hp-I is related with metabolic dysfunction-related fatty liver disease.•Hp-I is associated with Gal-3 overexpression.•Gal-3 appears to be an indicator of chronic kidney disease.•Hp, MetS and Gal-3 may contribute in liver, chronic kidney and brain disorders.•Hp-I may induce dysfunction of blood-brai...

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Published in:Metabolism, clinical and experimental clinical and experimental, 2021-05, Vol.118, p.154736-154736, Article 154736
Main Authors: Boziki, Marina, Polyzos, Stergios A., Papaefthymiou, Apostolis, Doulberis, Michael, Bakirtzis, Christos, Sintila, Styliani - Aggeliki, Touloumtzi, Maria, Grigoriadis, Nikolaos, Kountouras, Jannis
Format: Article
Language:English
Subjects:
Blood-brain-barrier
Brain Diseases
Galectin 3
Helicobacter Infections - complications
Helicobacter pylori
Humans
Kidney
Liver
Metabolic dysfunction-related fatty liver disease
Metabolic Syndrome
Neurodegenerative disease
Renal Insufficiency, Chronic
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Summary:•Hp-I is related with metabolic dysfunction-related fatty liver disease.•Hp-I is associated with Gal-3 overexpression.•Gal-3 appears to be an indicator of chronic kidney disease.•Hp, MetS and Gal-3 may contribute in liver, chronic kidney and brain disorders.•Hp-I may induce dysfunction of blood-brain-barrier.
ISSN:0026-0495
1532-8600
DOI:10.1016/j.metabol.2021.154736