Reductive Glycine Pathway: A Versatile Route for One-Carbon Biotech

Hong et al. heterologously expressed the metabolic core of the reductive glycine pathway (rGlyP) as a sink for the anaerobic conversion of glycerol. This recent study concludes several reports in 2020 on the ATP-efficient, one-carbon-assimilating rGlyP. Its engineering in diverse hosts could help th...

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Bibliographic Details
Published in:Trends in biotechnology (Regular ed.) 2021-04, Vol.39 (4), p.327-329
Main Author: Claassens, Nico J.
Format: Article
Language:English
Subjects:
Biotechnology
Carbon
Engineering
Enzymes
Glycerol
Glycine
Metabolism
Respiration
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Summary:Hong et al. heterologously expressed the metabolic core of the reductive glycine pathway (rGlyP) as a sink for the anaerobic conversion of glycerol. This recent study concludes several reports in 2020 on the ATP-efficient, one-carbon-assimilating rGlyP. Its engineering in diverse hosts could help the transformation toward renewable, one-carbon-based bioproduction.
ISSN:0167-7799
1879-3096
DOI:10.1016/j.tibtech.2021.02.005