Magnetic nanoparticles in developing electrochemical sensors for pharmaceutical and biomedical applications

• Published in: Talanta (Oxford) 2021-05, Vol.226, p.122108-122108, Article 122108
• Main Authors: Mollarasouli, Fariba, Zor, Erhan, Ozcelikay, Goksu, Ozkan, Sibel A.
• Format: Article
• Language: English
• Subjects: Biomarkers diagnosis; Biomedical; Electrochemical sensor; Gene Transfer Techniques; Genetic Therapy; Magnetic nanoparticles; Magnetics; Magnetite Nanoparticles; Pharmaceutical; Pharmaceutical Preparations
• ISSN: 0039-9140; 1873-3573
• DOI: 10.1016/j.talanta.2021.122108

A revolutionary impact on the pharmaceutical and biomedical applications has been arisen in the few years to come as a result of the advances made in magnetic nanoparticles (MNPs) research. The use of MNPs opens wide opportunities in diagnostics, drug and gene delivery, in vivo imaging, magnetic separation, and hyperthermia therapy, etc. Besides, their possible integration in sensors makes them an ideal essential element of innovative pharmaceutical and biomedical applications. Nowadays, MNPs-based electrochemical sensors have attracted great attention to pharmaceutical and biomedical applications owing to their high sensitivity, stability. Selectivity towards the target as well as their simplicity of manufacture. Therefore, this review focus on recent advances with cutting-edge approaches dealing with the synthesis, design, and advantageous analytical performance of MNPs in the electrochemical sensors utilized for pharmaceutical and biomedical applications between 2015 and 2020. The challenges existing in this research area and some potential strategies/future perspectives for the rational design of electrochemical sensors are also outlined. [Display omitted] •Assessment MNPs in electrochemical sensors.•Application of MNPs in pharmaceutical and biomedical field.•The synthesis of high-quality MNPs are very important for application of immunoassay.